Pharmaceutical Calculation Flashcards
What is the definition of a single dose?
Amount taken at one time
What is the definition of a daily dose?
Amount taken daily
What is the definition of a total dose?
The total amount given (relative to conversation, is it in a day, in a timeframe ect.)
What is the definition of a dose?
The quantity of drug to be delivered to a patient to achieve an intended effect
What is a dosing regimen?
The schedule of dosing (e.g., three time daily for 7 days)
What is dose based on?
• Biochemical and pharmacologic activity: ADME
• Physical and chemical properties: Hydrophilic, lipophilic
• Dosage form used: Tablet, capsule, transdermal patch, etc
• Route of Administration: PO, IV, etc
• Patient factors: Age, weight, body surface, liver and kidney function, etc
How do you calculate a dose?
To calculate a dose, you should multiple the dosage rate by the animal’s weight in kilograms (or pounds). The dose then is divided by the amount (concentration) of the drug in the pharmaceutic form (e.g., tablet or solution) to determine the actual amount of the pharmaceutic form to be administered.
Dose Measurement Example:
Does measurement example:
How do you convert lbs to kg?
Why do we use kg instead of lbs?
Because most scales used to weigh animals provide the weight in pounds, a conversion must be made from pounds to kilograms.
How do I determine the quantity of a drug to give a patient if I know how many total miligrams it needs in a dose?
If the order is to just “give a dog 300 mg of amoxicillin”, then the ordered amount is simply divided by the concentration of the drug to determine the amount to be administered
How do you calculate the number of doses needed/ the dispensing quantity?
Usually, you need to calculate the size of a dose, the number of doses, or the total quantity of drug to be dispensed.
Doses needed example: How many teaspoonfuls would be prescribed in each dose of an elixir if 180 mL contained in 18 doses?
Is there another equation used to calculate the number of doses needed/ the dispensing quantity?
Weight/ Volume Equivalents : FYI I think
Units of measure for Bio Sciences: FYI I think
Dose Measurement using body surface area
How do you find the dose based on BSA?
