Questions From lecture (Exam # 3) Flashcards
Alpha-1 receptors are associated with which one of the following effects?
a.) cardioacceleration
b.) vasodialation
c.) bronchodialation
d.) pupilary dilation
e.) pupilary constriction
d.) pupilary dilation
True or False: Terbutaline, a betat 2 agonist is considered a safe drug for an animal with cardiac disease.
True
Administration of which of the following NMB drugs will cause transient and painful skeletal muscle contractions?
a.) atracurium
b.) pancuronium
c.) vencuronium
d.) succinylcholine
e.) tubocurarine
d.) succinylcholine
Which of the following agent would you administer to reverse the action of nondepolarizing NMB drugs?
a.) gentamycin
b.) neomycin
c.) hemicholinium
d.) Neostigmine
d.) Neostigmine
True or False: AchE inhibitors act preventing acetyl choline release.
False
True or False: In patients with liver/ renal disease you would rather choose atracurium as a NMB drug.
True
True or False: Regarding to proton pump inhibitors, the binding to the carrier is irreversible and restoration of acid secretion requires the novo synthesis of ATPase by the parietal cell
True
True or False: SIBO effect may be a result of PPI administration.
TRUE
Substance P is an excitatory substance that increases secretion and motility of the GI tract. Which part of the ANS is being supported by this action?
a.) Sympathetic
b.) Parasympathetic
b.) Parasympathetic
True or False: Drugs that mimic the action of endogenous catecholamines are sympathomimetic drugs (adrenergic agonist). A direct-acting agonist helps reducing the metabolism of catecholamines.
FALSE
What is the primary neurotransmitter released from preganglionic neurons at sympathetic/parasympathetic ganglionic sites?
A.) NE
B.) EPI
C.) Ach
D.) Neuropeptide Y
C.) Ach
The anticipation of eating results in salivary secretion as response to a…
a.) parasympathetic stimulation
b.) sympathetic stimulation
a.) parasympathetic stimulation
Organophosphates are cholinesterase inhibitors and the poisoning can cause all of these actions except:
a.) Profuse salivation
b.) severe bronchoconstriction
c.) relaxation of GI smooth muscle
d.) urination
c.) relaxation of GI smooth muscle
Regarding to the use of NMB agents, which one of the following sentences is wrong?
a.) These agents increase the muscle relaxation
b.) An available apparatus for administering mechanical ventilation is always required
c.) Some of them are eliminated by Hofmann elimination.
d.) Prior administration of sedation or tranquilization is not necessary
d.) Prior administration of sedation or tranquilization is not necessary
True or False: Metoclopramide is useful for the treatment of a GI-obstruction.
FALSE
Which of the following H2-receptor antagonists does have also a prokinetic action on GI-tract.
a.) cimetidine
b.) ranitidine
c.) famotidine
b.) ranitidine
One of the big concerns of using erythromycin as a prokinetic drug is:
a.) to determine the right dose for achieving the desired effect.
b.) ensure the release of motilitin
c.) may cause diarrhea
d.) it can cause reflux esophagitis
c.) may cause diarrhea
Pilocarpine is a parasympathomimetic agent. Which responses do you expect to see following the administration of pilocarpine?
a.) decrease of peristaltic activity
b.) mydriatic effect
c.) Increased IOP
d.) Miosis effect
d.) Miosis effect
Terbutaline, albuterol, clenbuterol are selective adrenergic agonist to receptor(s) …
a.) Alpha-1
b.) Beta-1
c.) Alpha and beta 1
d.) Beta-2
d.) Beta-2
The vasoconstriction of blood vessel is a response to the stimulus of:
a.) isoproterenol
b.) dopamine
c.) phenylephrine
c.) phenylephrine
True or False: An individual endogenous catecholamine or sympathomimetic drug may exhibit a higher affinity or selectivity for one or more adrenergic receptor subtypes. EPI is one example of a very selective alpha-1 receptor agonist.
False
True or False: The chromaffin cells are innervated by parasympathetic preganglionic fibers
FALSE
True or False: The adrenal medulla secretes mostly NE and relatively little EPI
FALSE
