Questions From lecture (Exam # 3)

Question 1

Alpha-1 receptors are associated with which one of the following effects?
a.) cardioacceleration
b.) vasodialation
c.) bronchodialation
d.) pupilary dilation
e.) pupilary constriction

Answer 1

d.) pupilary dilation

Question 2

True or False: Terbutaline, a betat 2 agonist is considered a safe drug for an animal with cardiac disease.

Answer 2

True

Question 3

Administration of which of the following NMB drugs will cause transient and painful skeletal muscle contractions?
a.) atracurium
b.) pancuronium
c.) vencuronium
d.) succinylcholine
e.) tubocurarine

Answer 3

d.) succinylcholine

Question 4

Which of the following agent would you administer to reverse the action of nondepolarizing NMB drugs?
a.) gentamycin
b.) neomycin
c.) hemicholinium
d.) Neostigmine

Answer 4

d.) Neostigmine

Question 5

True or False: AchE inhibitors act preventing acetyl choline release.

Answer 5

False

Question 6

True or False: In patients with liver/ renal disease you would rather choose atracurium as a NMB drug.

Answer 6

True

Question 7

True or False: Regarding to proton pump inhibitors, the binding to the carrier is irreversible and restoration of acid secretion requires the novo synthesis of ATPase by the parietal cell

Answer 7

True

Question 8

True or False: SIBO effect may be a result of PPI administration.

Answer 8

TRUE

Question 9

Substance P is an excitatory substance that increases secretion and motility of the GI tract. Which part of the ANS is being supported by this action?
a.) Sympathetic
b.) Parasympathetic

Answer 9

b.) Parasympathetic

Question 10

True or False: Drugs that mimic the action of endogenous catecholamines are sympathomimetic drugs (adrenergic agonist). A direct-acting agonist helps reducing the metabolism of catecholamines.

Answer 10

FALSE

Question 11

What is the primary neurotransmitter released from preganglionic neurons at sympathetic/parasympathetic ganglionic sites?
A.) NE
B.) EPI
C.) Ach
D.) Neuropeptide Y

Answer 11

C.) Ach

Question 12

The anticipation of eating results in salivary secretion as response to a…
a.) parasympathetic stimulation
b.) sympathetic stimulation

Answer 12

a.) parasympathetic stimulation

Question 13

Organophosphates are cholinesterase inhibitors and the poisoning can cause all of these actions except:
a.) Profuse salivation
b.) severe bronchoconstriction
c.) relaxation of GI smooth muscle
d.) urination

Answer 13

c.) relaxation of GI smooth muscle

Question 14

Regarding to the use of NMB agents, which one of the following sentences is wrong?
a.) These agents increase the muscle relaxation
b.) An available apparatus for administering mechanical ventilation is always required
c.) Some of them are eliminated by Hofmann elimination.
d.) Prior administration of sedation or tranquilization is not necessary

Answer 14

d.) Prior administration of sedation or tranquilization is not necessary

Question 15

True or False: Metoclopramide is useful for the treatment of a GI-obstruction.

Answer 15

FALSE

Question 16

Which of the following H2-receptor antagonists does have also a prokinetic action on GI-tract.
a.) cimetidine
b.) ranitidine
c.) famotidine

Answer 16

b.) ranitidine

Question 17

One of the big concerns of using erythromycin as a prokinetic drug is:
a.) to determine the right dose for achieving the desired effect.
b.) ensure the release of motilitin
c.) may cause diarrhea
d.) it can cause reflux esophagitis

Answer 17

c.) may cause diarrhea

Question 18

Pilocarpine is a parasympathomimetic agent. Which responses do you expect to see following the administration of pilocarpine?
a.) decrease of peristaltic activity
b.) mydriatic effect
c.) Increased IOP
d.) Miosis effect

Answer 18

d.) Miosis effect

Question 19

Terbutaline, albuterol, clenbuterol are selective adrenergic agonist to receptor(s) …
a.) Alpha-1
b.) Beta-1
c.) Alpha and beta 1
d.) Beta-2

Answer 19

d.) Beta-2

Question 20

The vasoconstriction of blood vessel is a response to the stimulus of:
a.) isoproterenol
b.) dopamine
c.) phenylephrine

Answer 20

c.) phenylephrine

Question 21

True or False: An individual endogenous catecholamine or sympathomimetic drug may exhibit a higher affinity or selectivity for one or more adrenergic receptor subtypes. EPI is one example of a very selective alpha-1 receptor agonist.

Answer 21

False

Question 22

True or False: The chromaffin cells are innervated by parasympathetic preganglionic fibers

Answer 22

FALSE

Question 23

True or False: The adrenal medulla secretes mostly NE and relatively little EPI

Answer 23

FALSE