Pharm lll

Question 1

Tetracyclines 2

Answer 1

doxycylcine
minocycline 
broad spectrum
watch your bones/teeth, photosensitivity, prolongs QT
CI in children < 8 yo

Question 2

Isoniazid, Nydrazid

Answer 2

mycolic acid synthesis inhibitor

TB -polypharm (rifampin, pyrazinamide, isoniazid)

Question 3

TRIPLE ANTIBIOTIC

Answer 3

murine monomer synth inhibitor
neomycin, polymyxin B, Bacitracin

TOPICAL

Question 4

Cephalexin, Cefdinir

others (Ceftriaxone, Cefuroxime)

Answer 4

cephalosporin
1st, 3rd gen
Cephalexin: UTI, skin & soft tissue infxn (cellulitis)
Cefdinir: resistant to many B-lactamases

Question 5

Cell wall synthesis inhibitors types

Answer 5

1. penicillins
2. cephalosporins
3. glycopeptides

Question 6

Penicillin V

Answer 6

more narrow spectrum than others - ORAL only; broken down by beta-lactamases

Question 7

Broad spectrum penicillin for both gram pos and neg

Answer 7

ampicillin, amoxacillin, amoxicillin/clavulanate

INDIC: uncomplicated ENT infxn, h pylori

Question 8

Rifaximin Vs Rifampin

Answer 8

Rifax - monoxycarbolic acid agent / RNA inhibit

Rifamp - anti TB

Question 9

antibacterial glycopeptide

Answer 9

Vancomycin

Question 10

Macrolides all have what in their name?

Answer 10

ithro
ythro
(azithro, clarithro, erythro)

Question 11

Salmterol

ADR

Answer 11

LABA

prolongs QT

Question 12

Allegra generic

Answer 12

Fexofenadine

Question 13

Zyrtec generic

Answer 13

Cetirizine

Question 14

Claritin generic

Answer 14

loratidine

Question 15

1st gen anti-histamines are… 3

Answer 15

anti-cholinergics 
diphenhydramine
hydroxyzine
promethazine
- can be used for serotonin syndrome

Question 16

2nd gen anti-histamines

SE

Answer 16

loratadine
cetirizine
fexofenadine 
SE: prolong QT
inhibits cyp 450

Question 17

Benzonatate

Answer 17

cough suppressant

related to procaine

Question 18

dextromethorphan
codeine
hydrocodone

Answer 18

opioid anti-tussives

cough

Question 19

Sumatriptan MOA

Answer 19

5-HT1 agonist

migraine

Question 20

varenicline

Answer 20

aka chantix
stop smoking
partial nicotine agonist
BB warning -mental health

Question 21

zolpidem

Answer 21

zzzz- for sleep
ambien
interacts w GABA-BZ -receptors

Question 22

2 SNRI’s

Answer 22

duloxetine, venlafaxine
(cymbalta, effexor)
MDD
dulox is also used for GAD, diabetic peripheral neuropathy, chronic MSK pain

Question 23

Trazodone

Answer 23

SARI, serotonin antag and reuptake inhibitor

MDD, insomnia (off label)

Question 24

Mirtazapine

Answer 24

aka remeron, Tetracyclic
MDD
MOA unknwn

Question 25

Amitriptyline

Answer 25

tricyclic antidepressant
aka elavil
MOA unknown
indic Depression