Pharm lll Flashcards
Tetracyclines 2
doxycylcine minocycline broad spectrum watch your bones/teeth, photosensitivity, prolongs QT CI in children < 8 yo
Isoniazid, Nydrazid
mycolic acid synthesis inhibitor
TB -polypharm (rifampin, pyrazinamide, isoniazid)
TRIPLE ANTIBIOTIC
murine monomer synth inhibitor
neomycin, polymyxin B, Bacitracin
TOPICAL
Cephalexin, Cefdinir
others (Ceftriaxone, Cefuroxime)
cephalosporin
1st, 3rd gen
Cephalexin: UTI, skin & soft tissue infxn (cellulitis)
Cefdinir: resistant to many B-lactamases
Cell wall synthesis inhibitors types
- penicillins
- cephalosporins
- glycopeptides
Penicillin V
more narrow spectrum than others - ORAL only; broken down by beta-lactamases
Broad spectrum penicillin for both gram pos and neg
ampicillin, amoxacillin, amoxicillin/clavulanate
INDIC: uncomplicated ENT infxn, h pylori
Rifaximin Vs Rifampin
Rifax - monoxycarbolic acid agent / RNA inhibit
Rifamp - anti TB
antibacterial glycopeptide
Vancomycin
Macrolides all have what in their name?
ithro
ythro
(azithro, clarithro, erythro)
Salmterol
ADR
LABA
prolongs QT
Allegra generic
Fexofenadine
Zyrtec generic
Cetirizine
Claritin generic
loratidine
1st gen anti-histamines are… 3
anti-cholinergics diphenhydramine hydroxyzine promethazine - can be used for serotonin syndrome
2nd gen anti-histamines
SE
loratadine cetirizine fexofenadine SE: prolong QT inhibits cyp 450
Benzonatate
cough suppressant
related to procaine
dextromethorphan
codeine
hydrocodone
opioid anti-tussives
cough
Sumatriptan MOA
5-HT1 agonist
migraine
varenicline
aka chantix
stop smoking
partial nicotine agonist
BB warning -mental health
zolpidem
zzzz- for sleep
ambien
interacts w GABA-BZ -receptors
2 SNRI’s
duloxetine, venlafaxine
(cymbalta, effexor)
MDD
dulox is also used for GAD, diabetic peripheral neuropathy, chronic MSK pain
Trazodone
SARI, serotonin antag and reuptake inhibitor
MDD, insomnia (off label)
Mirtazapine
aka remeron, Tetracyclic
MDD
MOA unknwn
Amitriptyline
tricyclic antidepressant
aka elavil
MOA unknown
indic Depression
