Pharm l Flashcards
Drug for dry eyes
Cyclosporine
2 drugs for eye infxn & 1 combo drug
gentamicin, sulfacetamide
neomycin, polymyxin B, hydrocortisone
Used for swimmer’s ear infx
neomycin, polymyxin B, hydrocortisone
BB for glaucoma
timolol
cholinergic agonist for glaucoma
pilocarpine
PG analog for glaucoma
latanoprost
Eye pain drug
nepafenac
nasally inhaled steroids: 4
beclomethasone
budesonide
fluticasone
mometasone
4 allergy drugs for nose and types
mast cell
antihistamine
2 decongestants
cromolyn sodium - mast cell
olopatadine - antihistamine
oxymetazoline - decongestant
phenylephrine - decongestant
What is fluocinonide and clobetasol propionate
topical steroids
topical anti-psoriatic
calciptriol (synthetic vitamin D)
Types of Anti-Coagulants
anti-platelet vit K recycling antagonist xanthine derivative factor X inactivator factor Xa inactivator direct thrombin inhibitor
direct thrombin inhibitor
dabigatran
factor Xa inactivator
rivaraxaban
factor X inactivator
category X
heparin, enoxaparin
xanthine derivative
PAD, intermittent claud
pentoxifylline
vit K recycling antagonist
warfarin
anti-platelet
clopidogrel, aspirin
DMPS chelates…
merc, gold, arsenic
Deferoxamine chelates
iron
DMSA chelates
lead, merc, arsenic, antimony
EDTA chelates
merc, lead, iron
penicillamine chelates
Copper, and others
Sulfonylurea Tx Type ll Diabetes
Glyburide
hba1c reduces 1-2%
Besides metformin what other type 2 diabetes drug lowers hba1c 1.5-2%?
pioglitazone - a thiazolidinedione
GLP1 agonist tx type 2 Diabetes
liraglutide
decrease hba1c 1%
SGLT2 antagonist Tx type 2 diabetes
ADR
canaglifozin
canagliflozin ADR
- trench crotch
pioglitazone ADR
BB warning!! HT failure, bladder cancer
CYP2C8
Glyburide ADR
photosens, skin rash, GI probs, weight gain
DPP-4 inhibitor tx Type 2 Diabetes
sitagliptan
prolongs incretin levels
birth control hormones combined with ethinyl estradiol (3)
drospirenone (yaz)
norgestimate
norelgestromin (patch)
What is the name of patch form of contraceptive
norelgestromin (patch)
mini pill has how much progestin?
0.03 mg
plan B how much progestin?
1.5mg
What progestin is used alone or combined w E to tx menopause and as a OCP
norethindrone
Tx endometrial hyperplasia, secondary amen, and bleeding from fibroids?
progesterone and medroxyprogesterone acetate
A mineralocorticoid tx addisons
fludrocortisone
SE of nitrates is ?
HA
What is flecainide?
NA channel blocker - tx HTN
black box! increases mortality
Non-selective BB (2) Selective BB (2)
selective B-1 = atenolol, metoprolol
non-selective = propanolol, carvedilol
Amiodarone type
Tx what?
ADR’s
K+ channel blocker (potassium)
V-tach, V-fib
ADR: lung toxicity, hyper/hypo-thyroid bc looks like it, AV block, bradycardia, LR
CCB used to lower BP (3)
amlodipine
diltiazem
verapamil
Digoxin indic
HF, afib, ventricles
decreases HR and inotropic
HCTZ treats what?
ADRS
chronic HTN
ADR’s: closed angle glaucoma, GI, weakness, dizzy, thirsty
What is Triamterene?
K sparing diuretic
What is a bile acid sequestrant?
colesevelam
Gemfibrozil ADR’s
DVT, PE, increased homocysteine
STATIN enzyme metabolizer
CYP 450
Atorvastain C/I
ADR
C/I - LR Dz, preg (catX)
ADR - neuropathy, rhabdo, memory loss
ACE-I ADR other than cough
angioedema
Ramipril indic
ADR
HT failure after MI
ADR: hyperkalemia, acute renal failure
ARBS to Tx HTN (3) and Indic
Valsartan - HF
Irbesartan - nephropathy DM 2
Losartan - neophrapthy DM 2, LVH
Other Vasodilator
Hydralazine
What are doxazosin and terazosin
ADR
alpha-1 antagonist
decrease NE, Tx BPH
ADR - syncope, priapism, asthenia
what is clonidine
alpha 2 agonist - centrally acting
decreases NE
3 drugs for dementia
donepezil (C), memantine, rivastigmine
Types of drugs for epilepsy
GABA analogue
Sodium channel blocker
benzo
others: lamotrigine, topiramate, valproate
Types of Drugs for parkinson’s
dopamine precursor, agonist, anticholinergics, others (amantadine, diphenhydramine)
3 anticonvulsants used for bipolar
lamotrigine, valproate, carbamazepine
3 antipsychotics used for bipolar
risperidone, aripiprazole, quetiapine
a non-BZD anxiolytic
buspirone
MAO-I inhibitor indic for depression
phenelzine
Tetracyclic indic for depression
mirtazapine
2 SNRI for depression
duloxetine, venlafaxine
Donepezil and Rivastigmine or anti-alzheimer’s drugs. MOA?
AChe inhibitors
symptom control only
Memantine MOA
blocks NMDA-type glutamate receptors (glutamatergic excitotoxicity)