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*KS NPLEX ll > Pharm l > Flashcards

Pharm l Flashcards

1
Q

Drug for dry eyes

A

Cyclosporine

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2
Q

2 drugs for eye infxn & 1 combo drug

A

gentamicin, sulfacetamide

neomycin, polymyxin B, hydrocortisone

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3
Q

Used for swimmer’s ear infx

A

neomycin, polymyxin B, hydrocortisone

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4
Q

BB for glaucoma

A

timolol

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5
Q

cholinergic agonist for glaucoma

A

pilocarpine

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6
Q

PG analog for glaucoma

A

latanoprost

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7
Q

Eye pain drug

A

nepafenac

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8
Q

nasally inhaled steroids: 4

A

beclomethasone
budesonide
fluticasone
mometasone

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9
Q

4 allergy drugs for nose and types
mast cell
antihistamine
2 decongestants

A

cromolyn sodium - mast cell
olopatadine - antihistamine
oxymetazoline - decongestant
phenylephrine - decongestant

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10
Q

What is fluocinonide and clobetasol propionate

A

topical steroids

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11
Q

topical anti-psoriatic

A

calciptriol (synthetic vitamin D)

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12
Q

Types of Anti-Coagulants

A 
anti-platelet
vit K recycling antagonist
xanthine derivative
factor X inactivator
factor Xa inactivator 
direct thrombin inhibitor
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13
Q

direct thrombin inhibitor

A

dabigatran

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14
Q

factor Xa inactivator

A

rivaraxaban

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15
Q

factor X inactivator

category X

A

heparin, enoxaparin

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16
Q

xanthine derivative

PAD, intermittent claud

A

pentoxifylline

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17
Q

vit K recycling antagonist

A

warfarin

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18
Q

anti-platelet

A

clopidogrel, aspirin

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19
Q

DMPS chelates…

A

merc, gold, arsenic

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20
Q

Deferoxamine chelates

A

iron

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21
Q

DMSA chelates

A

lead, merc, arsenic, antimony

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22
Q

EDTA chelates

A

merc, lead, iron

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23
Q

penicillamine chelates

A

Copper, and others

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24
Q

Sulfonylurea Tx Type ll Diabetes

A

Glyburide

hba1c reduces 1-2%

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25
Q

Besides metformin what other type 2 diabetes drug lowers hba1c 1.5-2%?

A

pioglitazone - a thiazolidinedione

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26
Q

GLP1 agonist tx type 2 Diabetes

A

liraglutide

decrease hba1c 1%

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27
Q

SGLT2 antagonist Tx type 2 diabetes

ADR

A

canaglifozin

28
Q

canagliflozin ADR

A
  • trench crotch
29
Q

pioglitazone ADR

A

BB warning!! HT failure, bladder cancer

CYP2C8

30
Q

Glyburide ADR

A

photosens, skin rash, GI probs, weight gain

31
Q

DPP-4 inhibitor tx Type 2 Diabetes

A

sitagliptan

prolongs incretin levels

32
Q

birth control hormones combined with ethinyl estradiol (3)

A

drospirenone (yaz)
norgestimate
norelgestromin (patch)

33
Q

What is the name of patch form of contraceptive

A

norelgestromin (patch)

34
Q

mini pill has how much progestin?

A

0.03 mg

35
Q

plan B how much progestin?

A

1.5mg

36
Q

What progestin is used alone or combined w E to tx menopause and as a OCP

A

norethindrone

37
Q

Tx endometrial hyperplasia, secondary amen, and bleeding from fibroids?

A

progesterone and medroxyprogesterone acetate

38
Q

A mineralocorticoid tx addisons

A

fludrocortisone

39
Q

SE of nitrates is ?

A

HA

40
Q

What is flecainide?

A

NA channel blocker - tx HTN

black box! increases mortality

41
Q 
Non-selective BB (2)
Selective BB (2)
A

selective B-1 = atenolol, metoprolol

non-selective = propanolol, carvedilol

42
Q

Amiodarone type
Tx what?
ADR’s

A

K+ channel blocker (potassium)
V-tach, V-fib
ADR: lung toxicity, hyper/hypo-thyroid bc looks like it, AV block, bradycardia, LR

43
Q

CCB used to lower BP (3)

A

amlodipine
diltiazem
verapamil

44
Q

Digoxin indic

A

HF, afib, ventricles

decreases HR and inotropic

45
Q

HCTZ treats what?

ADRS

A

chronic HTN

ADR’s: closed angle glaucoma, GI, weakness, dizzy, thirsty

46
Q

What is Triamterene?

A

K sparing diuretic

47
Q

What is a bile acid sequestrant?

A

colesevelam

48
Q

Gemfibrozil ADR’s

A

DVT, PE, increased homocysteine

49
Q

STATIN enzyme metabolizer

A

CYP 450

50
Q

Atorvastain C/I

ADR

A

C/I - LR Dz, preg (catX)

ADR - neuropathy, rhabdo, memory loss

51
Q

ACE-I ADR other than cough

A

angioedema

52
Q

Ramipril indic

ADR

A

HT failure after MI

ADR: hyperkalemia, acute renal failure

53
Q

ARBS to Tx HTN (3) and Indic

A

Valsartan - HF
Irbesartan - nephropathy DM 2
Losartan - neophrapthy DM 2, LVH

54
Q

Other Vasodilator

A

Hydralazine

55
Q

What are doxazosin and terazosin

ADR

A

alpha-1 antagonist
decrease NE, Tx BPH
ADR - syncope, priapism, asthenia

56
Q

what is clonidine

A

alpha 2 agonist - centrally acting

decreases NE

57
Q

3 drugs for dementia

A

donepezil (C), memantine, rivastigmine

58
Q

Types of drugs for epilepsy

A

GABA analogue
Sodium channel blocker
benzo
others: lamotrigine, topiramate, valproate

59
Q

Types of Drugs for parkinson’s

A

dopamine precursor, agonist, anticholinergics, others (amantadine, diphenhydramine)

60
Q

3 anticonvulsants used for bipolar

A

lamotrigine, valproate, carbamazepine

61
Q

3 antipsychotics used for bipolar

A

risperidone, aripiprazole, quetiapine

62
Q

a non-BZD anxiolytic

A

buspirone

63
Q

MAO-I inhibitor indic for depression

A

phenelzine

64
Q

Tetracyclic indic for depression

A

mirtazapine

65
Q

2 SNRI for depression

A

duloxetine, venlafaxine

66
Q

Donepezil and Rivastigmine or anti-alzheimer’s drugs. MOA?

A

AChe inhibitors

symptom control only

67
Q

Memantine MOA

A

blocks NMDA-type glutamate receptors (glutamatergic excitotoxicity)

*KS NPLEX ll (17 decks)

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