❤️ Pharm- Centrally Acting Sympathetic Agonists Flashcards
1
Q
Clonidine (catapres)
Guanfacine (tenex, intutiv)
Guanabenz
Methyldopa*
A
CASA
-cannot be used alone!!!
2
Q
MOA
A
⬇️ sympathetic outflow by stimulating presynaptic a2 receptors- turn off sympathetic outflow
- promotes nacl and h20 retention: pair with diuretic
3
Q
AEs
A
Sedation Depression Dry mouth Brady cards Orthostatic hypotension Constipation
4
Q
Methyldopa
A
Hepatotoxicty
Hemolytic anemia