❤️ Pharm- Centrally Acting Sympathetic Agonists Flashcards

1
Q

Clonidine (catapres)
Guanfacine (tenex, intutiv)
Guanabenz
Methyldopa*

A

CASA

-cannot be used alone!!!

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2
Q

MOA

A

⬇️ sympathetic outflow by stimulating presynaptic a2 receptors- turn off sympathetic outflow
- promotes nacl and h20 retention: pair with diuretic

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3
Q

AEs

A
Sedation
Depression 
Dry mouth 
Brady cards 
Orthostatic hypotension
Constipation
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4
Q

Methyldopa

A

Hepatotoxicty

Hemolytic anemia

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