Osteoperosis Flashcards
1
Q
Calcium supplements
A
-differ in the amount of calcium they contain
2
Q
Calcium acetate Calcium citrate Calcium lactate Calcium carbonate Calcium glubionate Tricalcium phosphate Calcium chloride * Calcium gluconate**
A
Calcium supplements
3
Q
Calcium chloride is given how?
A
IV only
4
Q
Calcium gluconate is given how?
A
IV and PO
5
Q
Ergocalciferol (liver met) Dihydrotachysterol (doesn't require renal met) Cholecalciferol (liver met) Doxercalciferol Calcifedol Pericalcitol Calcitrol
A
Vitamin D analogs
6
Q
Alendronate Etidronate Risedronate Zoledronate Ibandronate Pamidronate Tiludronate
A
Bisphosphonates
7
Q
Raloxifene (evista)
A
Other anti osteoporosis/Ca drug
- selective estrogen receptor modulator
- mimics estrogen effect on bone, lipids and blood clotting
- blocks effects on endometrium and boobs
- VTE risk
- cause hot flashes
8
Q
Calcium supplements * given with vitamin D only way they are absorbed
A
- limited absorption (Max 600)
- risk of hypercalcemia
- GI toxicity (n/v, constipation)
- CNS toxicity (lethargy)
- drug inx; Chelation- bind to other drugs
9
Q
Bisphosphonates
- work well
- not all are approved to treat OP
A
- work in bone matrix/ become part of the bone
- decrease osteoclast activity
- low bioavailability
- take on empty stomach
- avoid with calcium and antacids
10
Q
Bisphosphonates AEs
A
Musculoskeletal pain, ONJ, esophageal cancer, renal toxicity
- atypical fracture risk
- esophagitis risk
11
Q
Bisphosphonates Patient Education
A
- take on empty stomach
- take with big glass of water
- remain upright for 30 min
- avoid taking calcium and antacids
- tell dentist if taking these, risk of ONJ
- risk of atypical fractures
