Anti Seizure Drugs AEDs Flashcards
1
Q
Complicated PK
High interaction risk
Most with cns depressing: learning and cognition
A
Older AEDs
2
Q
Straight forward PK
Low drug interaction
Tolerated better than old AED
A
New AEDs
3
Q
Complicated PK IV must be given slowly Auto inducer Severe skin reaction Fosphenytoin is prodrug
A
Phenytoin
4
Q
Patients with Asian decent must have test done due to risk of skin infection
A
Carbamazepine
Old AED
5
Q
Used only for absent seizures
A
Ethosuximide
Old AED
6
Q
Phenytoin Carbamazepine Valproic acid Ethosuximide Phenobarbital Primidone
A
Old AEDs
7
Q
Non seizure uses Pain Migraines Weight loss Kidney stones Medibolic acidosis
A
Topiramate
New AED
8
Q
Rash is common
A
Lamotrigine
New AED
9
Q
Common use for nerve pain
Nystagmus
Drowsiness
A
Gabapentin
New AED
10
Q
Infantile spasms
Vision constriction
A
Vigabatrin
New AED
11
Q
Aplastic anemia
Hepatotoxic it’s
A
Felbamate
12
Q
Euphoria
A
Lacosamide
New AED
13
Q
Oxcarbazepine Lamotrigine Gabapentin Pregabalin Levetiracetam Topiramate Tiagabine Zonisamide Felbamate Vigabatrin Lacosamide Rufonamide Clobazam Ezogabine
A
New AEDs
14
Q
Fat soluble
Operate in CNS
Enhance GABA
Goal: stop the seizure
Cns: impaired speech, cognition
Dizziness, weakness
Suicide and pregnancy risk
A
All AEDs
