pharm 7 Flashcards

1
Q

endocrine

A

hormones produced by a ductless gland that secretes directly into the bloodstream

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2
Q

hormones

A

chemical messengers that have specialized functions in regulating the activities

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3
Q

master gland

A

pituitary gland

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4
Q

pituitary gland

A

regulates the function of the other glands

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5
Q

somatotropin (human growth hormone)

A

regulates growth

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6
Q

adrenocorticotropic hormone (ACTH)

A

diagnosis of adrenocrtical insufficiency

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7
Q

cortrosyn

A

synthetic peptide of ACTH

used for diagnosis of adrenocortical insufficiency

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8
Q

adrenal glands

A

secrete cortiosteroids

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9
Q

corticosteroids

A

act on the immune system to suppress the body’s response to infection or trauma

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10
Q

2 categories of corticosteroids

A

replacement therapy

anti inflammatory

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11
Q

some conditions corticosteroids treat

A

allergic reactions
COPD
skin conditions

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12
Q

long term use of cortiocosteroids

A

suppression of the pituitary gland

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13
Q

cortiocosteroid SE

A

ORGAN TRANSPLANT
delayed wound healing
osteoporosis
cushings syndrome

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14
Q

thyroid

A

regulating the rate of metabolism

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15
Q

hypothyroidism

A

most common thyroid problem

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16
Q

thyroid preparations

A

replacement therapy for hypothyroidism

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17
Q

antithyroid agents

A

relieve hyperthroidism symptoms for surgery

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18
Q

antithyroid example

A

methimazole (treatment of choice)

19
Q

diabetes mellitus

A

impaired metablism

20
Q

type 1

A

destruction of pancreatic beta cells

21
Q

type 2

A

characterized by insulin resistance and deficiency

22
Q

juvenile diabetes

A

type 1

23
Q

most common diabetes

A

types 2

24
Q

when is insulin required?

A

type 1

25
Q

how is insulin given?

A

sub q

26
Q

hyperglycemia

A

elevated blood glucose

27
Q

hypoglycemia

A

lower blood glucose

28
Q

what do sulfonylureas do?

A

increase insulin production and activity

29
Q

alpha gluosidase inhibitors

A

delay digestion of complex carbs

30
Q

biguanides

A

decrease hepatic glucose production and enhance insulin uptake in muscle tissue

31
Q

metformin

A

preferred initial first line monotherapy (biguanides)

32
Q

incretin therapies

A

mimic actions of incretin hormones (may be benefical)

33
Q

example of incretin therapies

A

januvia

34
Q

meglitinides

A

rapid onset and short duration of action

35
Q

what do meglitinides do?

A

produce insulin

36
Q

thiazolidinediones example

A

actos

37
Q

thiazolidinediones

A

lower blood glucose

38
Q

how should you stop corticosteroids?

A

taper or step down gradually

39
Q

cretinism

A

congenital

requires treatment to prevent mental retardation

40
Q

hyperthyroid

A

caused by graves disease

41
Q

lantus

A

long acting insulin

42
Q

hyperglycemia treatment

A

IV fluids

43
Q

hypoglycemia treatment

A

sugary drink and then protein