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Semester 2 > Pharm 5 > Flashcards

Pharm 5 Flashcards

1
Q

empiric

A

best guess based on history

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2
Q

resistance to drugs

A

frequent use

incomplete treatment

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3
Q

selection of anti-infective drugs

A 
site of the infection
status of hepatic/renal failure
age
pregnancy
likelihood of develop resistance
known allergy
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4
Q

allergic hypersensitivtiy

A

over response of the body to a specific substance

mild: rash

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5
Q

anaphylaxis

A

severe reaction

dyspnea, chest constriction, shock

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6
Q

direct toxicity

A

results in tissue damage

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7
Q

indirect toxicity (superinfection)

A

new infection as a result of killing the normal flora

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8
Q

CDC recommendations

A

routine vaccines

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9
Q

aminoglycosides

A

treat gram - (E. Coli). gram + (Staph.)

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10
Q

treatment of septicemia

A

aminoglycosides

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11
Q

septicemia

A

bacteria in the bloodstream causing very low blood pressure

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12
Q

aminoglycosides side effects

A

nephrotoxicity

ototoxicity

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13
Q

cephalosporins

A

beta lactam antibiotic derivatives produced by a fungus BROAD

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14
Q

1st generation

A

UTI’s

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15
Q

2nd generation

A

bacterial pneumonia

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16
Q

3rd generation

A

STI’s

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17
Q

5th generation

A

acute bacterial skin

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18
Q

cephalosporins side effects

A

hypersensitiity

blood dyscrasias

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19
Q

macrolides

A

treatment of infections of the respiratory tract PREFFERED

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20
Q

macrolides side effects

A

superinfections

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21
Q

penicillins

A

treat strep. and staph. infections

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22
Q

drug of choice for syphilis

A

penicillin

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23
Q

prevent fevers

A

penicillin

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24
Q

penicillins side effects

A

superinfections

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25
Q

carbapenems

A

beta lactam class of antiiotics

26
Q

carbapenems treatment

A

pneumonia BROAD

27
Q

quinolones

A

adult UTI’s

28
Q

quinolones side effects

A

phototoxicity

cartilage or tendon damage

29
Q

tetrcyclines

A

treat infections caused by rickettsia, chlamydia BROAD

30
Q

tetracyclines side effects

A

discolored teeth in young children

31
Q

amphotericin B

A

administered by IV for fatal infections

32
Q

drug of choice fore severe fungal infections

A

amphotericin

33
Q

amphotericin side effects

A

watch closer since severe

34
Q

fluconazole

A

antifungal agent treatment of oropharyngeal and esophageal candidiasis

35
Q

fluconazole side effects

A

hepatic abnormalities

36
Q

antifungals

A

treat fungal disease

37
Q

micafungin

A

newer classes of antifungals IV

38
Q

micafungin treatment

A

esophageal candidiasis and aspergillus

39
Q

micafungin side effects

A

neutropenia

40
Q

nystatin

A

orally teat oral cavity candidiasis

41
Q

clindamycin

A

serious respiratory tract infections, septemia

42
Q

metronidazole

A

treatment for amebiasis and giardiasis

43
Q

metronidazole side effect

A

dark urine

44
Q

vancomycin

A

drug of choice for MRSA

45
Q

last line of defense

A

vancomycin for staph.

46
Q

linezolid

A

gram + infections

VRE VRSA

47
Q

diabetic foot infections

A

linezolid

48
Q

sulfonamides

A

oldest anti infectives

good when put with other drugs; less resistance then

49
Q

sulfonamides side effects

A

hepatic toxicity

renal damage

50
Q

UTI

A

most common

microorganisms in the urinary tract

51
Q

sulfamethoxazole trimethoprim and nitrofurantoin

A

first line urinary anti infectives for empiric treatment

52
Q

UTI side effects

A

dark yellow urine

53
Q

acyclovir

A

treat herpes simplex, shingles, and chickenpox

54
Q

acyclovir side effects

A

lethargy

tremors

55
Q

neuraminidase inhibitors

A

treatment of uncomplicated illness due to influenza A and B

56
Q

neuraminidase inhibitors

A

airway irriation since it is done by inhalation

57
Q

ribavirin

A

BROAD

treatment of children with respiratory syncytial virus infections

58
Q

macrolides preferred

A

least toxic and preferred for pregnant women or infants

59
Q

poses greater risk for superinfection

A

tetracyclines

60
Q

cephalosporins bad

A

alcohol

61
Q

related to penicillins

A

cephalosporins

Semester 2 (26 decks)

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