Peptic Ulcer Disease Flashcards

1
Q

Aetiologies?

A
H. PYLORI INFECTION
NSAIDs 
Zollinger-Ellison syndrome
Hyperparathyroidism
Crohn's 
Increased gastric emptying (DU)
Smoking (GU)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pathology?

A

Chronic inflammation of areas colonised by H. pylori –> acid erosion
Acid erosion of normal mucosa by other causes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Signs and Symptoms?

A
Epigastric pain +/- tenderness
Nocturnal hunger/pain (DU)
Back pain (DU)
N+V 
Weight loss
Haematemesis 
Melaena
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Investigations and Findings?

A

Test for H. pylori - positive if infection

Upper GI endoscopy - visualise ulceration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Management?

A

Avoid causative foods and smoking
Treat H. pylori - triple therapy (clarithromycin, amoxicillin and PPI)
Stop NSAIDs
Surgical management is last resort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Complications?

A

Scarring
Acute bleed
Perforation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly