Gastro-Oesophageal Reflux Disease Flashcards
1
Q
Aetiologies?
A
Anything which impairs LOS Drugs Pregnancy Smoking Obesity Hypomotility Alcoholism
2
Q
Pathology?
A
Increased LOS relaxations/delayed gastric or oesophageal emptying/decreased resistance to bile and acid
3
Q
Signs and Symptoms?
A
Heartburn Belching Acid brash Water brash Odynophagia Cough Laryngitis
4
Q
Investigations and Findings?
A
Not required in isolated cases
Upper GI endoscopy in presence of alarm features
Can show breaks in longitudinal muscle, hiatus hernia
5
Q
Management?
A
Lifestyle alteration
Antacids
PPIs in oesophagitis
Fundoplication in severe disease
6
Q
Complications?
A
Barrett’s oesophagus
Adenocarcinoma