Chronic Liver Disease Flashcards

1
Q

Aetiologies?

A
Alcoholism
NASH
Viral hepatits 
Leptospirosis 
Paracetamol overdose
Primary biliary cirrhosis 
Haemachromatosis
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2
Q

Signs and Symptoms?

A

Asymptomatic until major complications arise, RUQ pain, Ankle oedema, Distension, Haematemesis, Pruritus, Gynaecomastia, Confusion/fatigue
Spider naevi, palmar erythema, clubbing, Dupuytren’s contracture, Xanthomas, Hepatomegaly, Splenomegaly, ascites, jaundice, fever, hepatic flap

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3
Q

Investigations and Findings?

A
FBC - thrombocytopenia 
INR - increased 
ALT/AST - increased 
ALP
Bilirubin - increased 
Ammonia - increased 
Glucose - decreased
Serology
Doppler USS - small/large liver 
CT/MRI 
GGT - raised suggest alcoholism
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4
Q

Management?

A

Treat cause
ABCD resuss
Symptomatic relief
Treat complications

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5
Q

Complications?

A
Variceal bleeding --> shock
Cirrhosis 
Infection 
Sepsis 
Death
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