Peds rheumatology Flashcards
five cardinal signs of inflammation
calor, rubor, tumor, dolor, functio laesa
autoinflammatory vs autoimmune
inflam= innate IS (PMNs, macrophages), immune= adaptive IS (B, T cells)
summary of JIA
high spiking fever, arthritis, serositis, evanescent patchy rashes, generalized lymphadenopathy
summary of Kawasaki
high fever, polymorphous rashes, conjuctival and mucosal changes, edema of extremities, vervical lymphadeopathy
summary of HSP
palpable purpura, acute arthritis/arthralgia, abdominal pain, proteinuria
summary of juvenile dermatomyositis
Gottron’s papules, heliotrope rash, symmetric proximal weakness, elevated muscle enzymes
how do we often know if there are vascular problems?
skin is a window into the vasculature
sJIA buzz words
quotidian fever, evanescent rash. Rash coming out with fever is big clue.
Macrophage activation syndrome: seen in what? key characteristics
complication of sJIA. macrophages eating up blood cells: pancytopenia, sky high ferritin
strawberry tongue, rash on perineum
kawasaki
diagnosis of kawasaki: fever? rash? lymphadenopathy?
fever >5 days plus polymorphous rash, cervical lymphadenopathy
most common causes of sudden death in Kawasaki
carditis and aneurysm
HSP four signs
rash, arthritis, nephritis, abdominal pain (intussiception)
HSP: what is elevated and what is not
IgA is elevated. NO Thrombocytopenia!!
rash of juvenile dermatomyosits
on sun-exposed surfaces. (v on chest). heliotrope (around eyes). Gotton’s papules. Eyelid telangectasia
