Lupus Flashcards
population at highest risk for SLE
women in their reproductive years
Diagnosis of SLe
at least four of the 11 criteria
what are the eleven criteria for SLE
malar rash, discoid rash, photosensitivity, oral ulcers, arthritis, serositis, glomerulonephritis, neurologic disorder, hematologic disorder, ANA, immune disorder
Which autoantibodies are specific for SLE
anti-dsDNA (nephritis), Anti-Sm
which Aab signifies nephritis? clotting dz? dry eyes/mouth/photosensitivity? Arthritis/myositis/lung dz?
dsDNA; antiphospholipid; anti SSA and SSB; anti-RNP
leading causes of mortality in SLE
heart dz, malignancy, infection
side effects of immunosuppressants
infection, cancer, infertility
side effects of corticosteroids
infections, osteoporosis, hyperglycemia, hypertension