Peds GI Flashcards
necrotizing enterocolitis –> epidemiology?
- preterm
- term: congenital heart dz, immunosupp, umbilical venous catheter
necrotizing enterocolitis –> cause?
combo of infxn & ischemia related to feeding
necrotizing enterocolitis –> MC location?
ileum & RLQ colon
necrotizing enterocolitis –> initial XR finding
loop of bowel:
- wall thicken
- fixed distention over serial exams
necrotizing enterocolitis –> MC complication
bowel stricture
hypertrophic pyloric stenosis –> epidemiology?
2-12wk M>F
hypertrophic pyloric stenosis –> US findings? (3)
- thickened pylorus wall
- increased pyloric channel length
- gastric contents not pass thru
pylorospasm –> US findings?
- normal pylorus
- gastric contents pass thru
infant –> appendicitis –> common or rare?
rare
volvulus –> clinical presentation?
neonatal bilious emesis
malrotation –> MOA?
embryogenesis –> bowel fail to normally rotate
malrotation –> potential complication? (2) why?
- abnormal mesenteric fixation –> volvulus
- Ladd bands –> distal bowel obstruct
malrotation –> when present?
70% within 1mo
90% within 1yo
UGI –> eval for malrotation –> specific components to evaluate? (3)
- C-sweep of duodenum
- duodeno-jejunal jx: L of midline & at level of duodenal bulb
- 2nd & 4th duodenum retroperitoneal & parallel
midgut volvulus:
- MC XR appearance?
- uncommon XR appearance?
- MC XR appearance: mult dilated bowel loops
- uncommon XR appearance: duodenal obstruct –> double bubble sign
midgut volvulus –> classic UGI finding?
corkscrew appearance
malrotation –> cecum location?
- more midline than normal
- LLQ
malrotation –> SMA & SMV location?
normal: right SMV, left SMA
malrotation: right SMA, left SMV
malrotation –> tx?
Ladd procedure:
- reduce volvulus
- lyse mesenteric adhesions (Ladd bands)
- place small bowel on R, large bowel on L
intussusception –> MC location?
ileocolic
intussusception –> classic presentation?
- colicky abd pain
- currant jelly stool
- palpable RLQ abd mass
intussusception –> idiopathic vs pathologic lead point –> epidemiology?
- newborn: pathologic lead pt
- 3mo-3.5yo: idiopathic
- > 3.5yo: pathologic lead pt
neonate –> intussusception –> possible cause?
Meckel diverticulum
> 3.5yo –> intussusception –> possible cause?
lymphoma
bloody stool –> US demonstrate bowel wall thickening –> ddx? (3)
- intussusception
- colitis
- intramural hematoma (d/t trauma, Henoch-Schonlein purpura)
intussusception –> tx?
air/contrast enema
intussusception –> tx enema reduction –> contraindication? (3)
- free air
- peritoneal signs
- septic shock
esophageal atresia & tracheoesophageal fistula –> MC assoc synd?
VACTERL
VACTERL –> synd?
- Vertebral segmentation anomaly
- Anal atresia
- Cardiac anomaly
- TracheoEsophageal fistula
- Renal anomaly
- Limb (radial ray) anomaly
tracheoesophageal fistula –> MC type?
82% –> type A: proximal esophageal atresia & distal TEF
proximal esophageal atresia & distal TEF –> classic CXR appearance?
- NG tube terminate mid-esophagus
- air-filled bowel (from TEF)
TEF –> assoc condition?
tracheal anomaly:
- tracheomalacia
- bronchus suis
in utero –> polyhydramnios & lack of visualization of stomach –> ddx? (1)
esophageal atresia
gastric atresia –> diagnostic imaging finding?
single bubble
clinical presentation –> hypertrophic pyloric stenosis vs gastric atresia?
vomiting:
HPS: progressively worse
gastric atresia: not worse
neonatal bowel obstruct –> when present?
24-48 day old
XR –> proximal bowel obstruction –> next imaging modality of choice for evaluation? why?
UGI –> differentiate midgut volvulus (emergent surg) vs atresia (non-emergent)
XR –> distal bowel obstruction –> next imaging modality of choice for evaluation?
LGI
proximal bowel obstruction –> tx?
surg
distal bowel obstruction –> tx?
- surg
- medical
duodenal anomaly –> other assoc anomaly? (5)
- Down
- VACTERL
- cardiac shunt lesion
- malrotation
- annular pancreas
duodenal atresia –> classic XR appearance?
- double bubble: dilation stomach + proximal duodenum
- lack of distal bowel gas
double bubble + distal bowel gas –> ddx? (3)
- midgut volvulus
- annular pancreas
- duodenal stenosis/web
jejunal atresia –> MCC?
in utero vascular insult
jejunal atresia –> classic XR appearance?
triple bubble
distal bowel obstruction –> surgical causes? (2)
- distal atresia
- Hirschsprung dz
distal bowel obstruction –> medical causes? (2)
- meconium ileus
- fxal immaturity
what is microcolon?
abnormally small caliber (<1cm) colon –> d/t disuse
microcolon –> secondary to proximal vs distal bowel obstruction? why?
distal
proximal bowel –> secrete succus entericus –> prevent microcolon
microcolon –> MCC? (2)
- meconium ileus
- ileal atresia
microcolon –> ddx? (4)
- meconium ileus
- ileal atresia
- total colonic Hirschsprung
- megacystic-microcolon-hypoperistalsis synd
meconium ileus –> assoc calcifications can be seen where? (2) why?
- peritoneal
- scrotal
perforation –> meconium peritonitis –> calcifications
meconium ileus –> classic XR appearance?
- distal obstruction (mult dilated bowel)
- RLQ soap bubble lucencies
meconium ileus –> indicates what condition?
100% –> cystic fibrosis
meconium ileus –> LGI appearance? (2)
- microcolon
- mult rounded filling defects (inspissated meconium)
meconium ileus –> tx?
water-soluble enema –> loosen inspissated meconium
fail to pass meconium –> MC condition?
small left colon (fxal immaturity of the colon, meconium plug synd)
small left colon –> MOA?
colonic ganglion cells –> temporary fxal immaturity –> distal colon abnormal motility
small left colon –> risk factors? (3)
- preterm
- maternal Mg for preclampsia
- maternal diabetes
small left colon –> microcolon or no microcolon?
no microcolon
small left colon –> XR finding?
distal bowel obstruct
small left colon –> LGI finding?
- small left colon
- discrete transition pt at splenic flexure
- filling defects in small left colon –> meconium plugs
small left colon w discrete transition pt at splenic flexure –> ddx? (2) how to differentiate? (2)
small left colon:
- rectum distend
- resolve w enema
Hirschsprung dz:
- rectum nondistend
- not resolve w enema
Hirschsprung dz –> anus is always involved –> T/F?
T
Hirschsprung dz –> continuous or scattered bowel involvemt?
continuous
Hirschsprung dz –> possible complication?
1/3 –> enterocolitis, similar to NEC –> toxic megacolon
Hirschsprung dz –> XR finding?
distal bowel obstruction
Hirschsprung dz –> LGI finding
- dilated proximal bowel
- narrow distal bowel
- tapered “cone-shaped” transition
Hirschsprung dz –> rectum:sigmoid ratio?
<1
what is megacystic microcolon intestinal hypoperistalsis synd?
congenital loss of bowel & bladder smooth muscle fx:
- absent intestinal peristalsis
- microcolon
- distended nonobstructed urinary bladder
childhood bowel obstruction –> ddx? (6)
AAIIMM:
- appendicitis
- adhesions
- internal/inguinal hernia
- intussusception
- Meckels
- malrotation
indirect inguinal hernia –> MOA?
patent processus vaginalis –> peritoneal comm to scrotum
imperforate anus –> role of imaging? preferred imaging modality?
clinical dx
eval level of obstruct: high/low relative to puborectalis sling (however, this is usu determined clinically)
infracoccygeal US
high anorectal malformation –> assoc anomalies? (3)
- GU-rectal fistula
- lumbosacral anomaly
- VACTERL
high anorectal malformation –> type of GU-rectal fistula –> M vs F?
- M: rectum to post urethra or bladder
- F: rectum to vagina
low anorectal malformation –> assoc anomaly? (1)
perineal fistula
neonatal –> unconj hyperbili –> cause?
physiologic jaundice of newborn
neonatal –> conj hyperbili –> cause? (2)
- biliary atresia
- neonatal hepatitis (ie Alagille synd, bile acid synthetic defect, metabolic dz, AAT1 def, infx)
neonatal –> conj hyperbili –> goal of imaging? preferred imaging modality?
Tc-99m-HIDA hepatobiliary scintigraphy –> differentiate biliary atresia vs neonatal hepatitis
neonatal –> conj hyperbili –> premedication for HIDA scan? why? when?
5 days of phenobarbital –> stimulate hepatocyte activity
biliary atresia –> natural progression if untx?
progressive cirrhosis –> early childhood death
biliary atresia –> HIDA findings? (3)
- normal hepatic tracer uptake
- normal hepatic clearance
- no excretion into small bowel
biliary atresia vs neonatal hepatitis –> US appearance?
cannot differentiate
sometimes absent GB –> suggest biliary atresia
biliary atresia –> tx?
Kasai portoenterostomy:
- excise entire extrahep biliary tree
- jejunal loop anastomose to liver
neonatal hepatitis –> HIDA findings?
- poor hepatic excretion
- delayed hepatic clearance (>12hr)
- variable bowel excretion
primary cancers w liver mets? (4)
- neuroblastoma
- Wilms tumor
- sarcoma
- Burkitt lymphoma
what is mesenchymal hamartoma?
developmental anomaly (not neoplasm) –> multicystic hamartomatous lesion –> malformed bile ducts, portal vein fragmts, extramed hematopoiesis –> benign
mesenchymal hamartoma –> when present?
neonate
what is gallbladder hydrops? predisposing condition? (2)
pathologically distended GB
- infx
- systemic inflamm (ie Kawasaki)
vascular neoplasm vs malformation?
neoplasm: new cell growth
malformation: disorganized vasc; no cell growth
high flow vascular malformation/neoplasm? (3)
- infantile hemangioma
- AVM
- AV fistula
low flow vascular malformation? (2)
- venous malformation
- lymphatic malformation
adult –> hepatic hemangioma –> are actually venous malformation, T/F?
T
pediatric –> MC vascular hepatic tumor
infantile hemangioma & hemangioendothelioma
infantile hemangioma vs hemangioendothelioma?
hemangioma: benign
hemangioendothelioma: usu benign –> can mets
infantile hemangioma & hemangioendothelioma –> assoc synd? (1)
Kasabach-Merritt synd
Kasabach-Merritt synd –> synd? (3)
- vascular neoplasm
- hemolytic anemia
- consumptive coagulopathy
infantile hemangioma & hemangioendothelioma –> potential complication? (1)
25% –> congestive heart fail
infantile hemangioma & hemangioendothelioma –> MRI appearance (3)
- highly vascular
- T2 hyper
- enhance peripheral –> delayed fill-in
infantile hemangioma & hemangioendothelioma –> conventional angiography finding?
- enlrg celiac axis
- aorta distal to celiac trunk –> narrow
infantile hemangioma & hemangioendothelioma –> tx?
- most spontaneously involute within 1st yr of life
- BB –> accel involution
- surg if CHF
3 MC childhood abd malig
1) neuroblastoma
2) Wilms tumor
3) hepatoblastoma
hepatoblastoma –> when present, younger/older/same as infantile hemangioma?
slightly older
hepatoblastoma –> assoc synd? (3)
- Beckwith-Wiedemann
- familial adenomatous polyposis synd
- fetal alcohol synd
Beckwith-Wiedemann –> screen for what? how often?
hepatoblastoma –> q6mo
hepatoblastoma –> what lab is elevated?
alpha-fetoprotein (AFP)
hepatoblastoma –> classic XR finding?
RUQ calcification
hepatoblastoma –> CT appearance?
- predominantly solid heterogeneous enhancing liver mass
- like to invade portal & hepatic veins
pediatric –> cirrhosis –> causes? (5)
- AAT1 def
- glycogen storage dz
- tyrosinemia
- biliary atresia
- chronic viral hepatitis
HCC –> imaging appearance?
- heterogeneous hepatic mass
- early arterial enhance
- rapid washout
HCC –> AFP elevated or normal?
elevated
undifferentiated embryonal sarcoma (malig mesechymoma) –> epidemiology?
6-10yo
undifferentiated embryonal sarcoma (malig mesechymoma) –> AFP elevated or normal?
normal
liver mets –> primary? (2)
- neuroblastoma
- Wilms tumor
Meckel diverticulum –> MOA?
omphalomesenteric duct –> incomplete regress
Meckel diverticulum –> pediatric –> potential complication? (2)
- GI bleed (if contain ectopic gastric mucosa)
- lead pt –> intussusception
Meckel diverticulum –> adult –> potential complication? (2)
#1 SBO #2 Meckel diverticulitis
what is omphalomesenteric duct?
duct –> connect intestine to umbilicus/yolk sac
omphalomesenteric duct –> incomplete regress –> complication? (2)
- # 1 Meckel diverticulum
- umbilico-ileal fistula
Meckel diverticulum –> rule of 2’s?
- 2% population
- symptomatic before 2yo
- 2ft from ileocecal valve
rectal bleed –> suspect Meckel diverticulum –> imaging of choice?
Tc-99m pertechnetate scan
Tc-99m pertechnetate scan –> what tissue does it detect?
gastric mucosa
pediatric abd neoplasms w calcifications (3)
- neuroblastoma
- teratoma
- hepatoblastoma
pancreatoblastoma –> age?
1-8yo