Pathopharm 2 Exam 3 Flashcards
Which causes mycosis?
Fungi
T/F
Pandemic is across a continent?
True
T/F
Shingles disorder is caused by the reactivation of herpes virus?
True
T/F
The primary advantage of Rimantadine (Flumadine) over Amantadine (Symmetrel) is the greatly increased spectrum of antiviral activity ?
False
Rimantadine advantage is hepatic metabolism that avoids toxicity
T/F
Peramivir is used as flu prophylaxis?
False
Not prophylaxis, but decreases length of infection
HIV attacks which cell?
CD4+ T cells
T/F
Remdesivir is a protease inhibitor used to treat HIV ?
False
Treats COVID-19
T/F
Cyclophosphamide is a purine analog used to inhibit DNA synthesis ?
False
Its an alkylator used to cross-link DNA
T/F
5-Fluorouracil is a purine analog ?
False
It an analog of uracil
T/F
Bleomycin causes SIADH secretion ?
False
only Cyclophosphamide and Vincristine do
Which one of these has a half-life of 10 days?
a. none of these
b. linezolid
c. vancomyocin
None of the these
Paclitaxel, Docetaxel, and Carbazitael do all of the following except ?
Hepatic toxicity
T/F
Carboplatin has a longer half-life than Cisplatin ?
True
Which one of these is an iron source and enters cell?
Cefiderocol
T/F
(IA) should be avoided in cancer patients due to immunosuppression?
True
What is the drug of choice for Bordetella (whooping cough) ?
macrolides- erythromycin, clarithromycin, azithromycin
Which one of these is not a beta-lactam?
a. clarithromycin
b. vancomycin
c. cephalosporin
d. none of these
a. clarithromycin (macrolide)
T/F
Kernicterus is caused by bilirubin buildup?
True
T/F
The sulfonamide antibiotics are analogs of para-amino-benzoic-acid (PABA) ?
True
The flu is a?
1. virus
2. bacteria
3. fungi
Virus
T/F
OU abbreviation is both ears ?
False
Its both eyes
T/F
Legend drugs do not need a prescription for outpatient therapy, and only signature from the patient ?
False
Legend = Controlled substances
T/F
Ceftriaxone (Rocephin) is the drug of choice for gonorrhea infections ?
True
T/F
Glucose control decreases infection?
True
What is a risk in surgical patients with bone marrow depression ?
Infection
What Aldehyde that is a good disinfectant ?
Glutaraldehyde
T/F
Vertical transmission is an example of transmitting disease from mom to baby ?
True
T/F
Phosphodiesterase inhibitors are not used to treat HIV ?
True
All of these are ways HIV is transmitted except what?
a. urine
b. blood
c. semen
d. breast milk
a. urine
T/F
Clavulanic acid is used w/Amoxicillin in Augmentin to slow the rate of renal secretion of Amoxicillin.
False
T/F
Ampicillin is the drug of choice to treat infections due to Pseudomonas aeruginosa?
False
Ciprofloxacin is drug of choice for P aer
Which of the following antibiotics is considered to possess the greatest level of neuromuscular blockade?
Telithromycin (Ketek)
Black box warning with Myasthenia Gravis patients
T/F
Pseudomembranous colitis is caused by a bacterial toxin and is best treated with Clindamycin (Cleocin) ?
False C-dif best treated with oral Vanco
Which of the following compounds is not used as an antiseptic?
Ethylene Oxide (Its a disinfectant)
T/F
Ribavirin (Virazole) has been shown to shorten the duration of viral pneumonia infections ?
True
T/F
Cyclophosphamide (Cytoxan) acts to kill cancer cells by substituting for purines in DNA synthesis ?
False
T/F
Highly active antiretroviral therapy (HAART) is a therapeutic method primarily used to treat various body cancers ?
False, it treats HIV
T/F
A sarcoma is a cancer of cells in the bloodstream ?
False
T/F
Most antiseptics act by altering the structure &/or function of the bacterial cell wall ?
True
T/F
The varicella-zoster virus is responsible for causing shingles ?
True
T/F
Genital herpes (type II) can be cured by a five day regimen of Valacyclovir (Valtrex) therapy ?
False
NO CURE, helps treat pain
Which of the following enzymes converts single stranded RNA into DNA ?
Reverse Transcriptase
Which of the following virus’ is believed to cause Burkitt’s lymphoma?
None of these answers are correct
It is caused by Epstein-Barr virus
T/F
Isopropyl alcohol is ineffective as an antiseptic against most viral organisms.
True
It kills bacteria, NOT virus’ or fungal
T/F
Methotrexate is an analog of folic acid?
True
T/F
Bone marrow depression is a common DLT in anticancer therapy ?
True
T/F
Care should be taken during GA in pts who have been taking Busulfan (Myleran) due to an enhanced risk of pulmonary complications ?
True
T/F
HIV reverse transcriptase acts to insert the viral DNA into the host cell DNA ?
False
What is the main difference between Amantadine and Rimantadine ?
Hepatic metabolism- Rimantadine
Which antibiotic has Gray baby syndrome adverse effect?
Chloramphenicol
What is over the counter medication to treat UTI painful symptoms for women?
Phenazopyridine
How many days does it take for HIV antibodies to show up in a lab test?
25 days
What is a new aminioglycoside for treating complicated UTIs?
Plazomicin
