Pathopharm 2 Exam 3 Flashcards

1
Q

Which causes mycosis?

A

Fungi

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2
Q

T/F
Pandemic is across a continent?

A

True

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3
Q

T/F
Shingles disorder is caused by the reactivation of herpes virus?

A

True

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4
Q

T/F
The primary advantage of Rimantadine (Flumadine) over Amantadine (Symmetrel) is the greatly increased spectrum of antiviral activity ?

A

False
Rimantadine advantage is hepatic metabolism that avoids toxicity

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5
Q

T/F
Peramivir is used as flu prophylaxis?

A

False
Not prophylaxis, but decreases length of infection

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6
Q

HIV attacks which cell?

A

CD4+ T cells

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7
Q

T/F
Remdesivir is a protease inhibitor used to treat HIV ?

A

False
Treats COVID-19

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8
Q

T/F
Cyclophosphamide is a purine analog used to inhibit DNA synthesis ?

A

False
Its an alkylator used to cross-link DNA

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9
Q

T/F
5-Fluorouracil is a purine analog ?

A

False
It an analog of uracil

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10
Q

T/F
Bleomycin causes SIADH secretion ?

A

False
only Cyclophosphamide and Vincristine do

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11
Q

Which one of these has a half-life of 10 days?
a. none of these
b. linezolid
c. vancomyocin

A

None of the these

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12
Q

Paclitaxel, Docetaxel, and Carbazitael do all of the following except ?

A

Hepatic toxicity

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13
Q

T/F
Carboplatin has a longer half-life than Cisplatin ?

A

True

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14
Q

Which one of these is an iron source and enters cell?

A

Cefiderocol

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15
Q

T/F
(IA) should be avoided in cancer patients due to immunosuppression?

A

True

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16
Q

What is the drug of choice for Bordetella (whooping cough) ?

A

macrolides- erythromycin, clarithromycin, azithromycin

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17
Q

Which one of these is not a beta-lactam?
a. clarithromycin
b. vancomycin
c. cephalosporin
d. none of these

A

a. clarithromycin (macrolide)

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18
Q

T/F
Kernicterus is caused by bilirubin buildup?

A

True

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19
Q

T/F
The sulfonamide antibiotics are analogs of para-amino-benzoic-acid (PABA) ?

A

True

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20
Q

The flu is a?
1. virus
2. bacteria
3. fungi

A

Virus

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21
Q

T/F
OU abbreviation is both ears ?

A

False
Its both eyes

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22
Q

T/F
Legend drugs do not need a prescription for outpatient therapy, and only signature from the patient ?

A

False
Legend = Controlled substances

23
Q

T/F
Ceftriaxone (Rocephin) is the drug of choice for gonorrhea infections ?

A

True

24
Q

T/F
Glucose control decreases infection?

A

True

25
Q

What is a risk in surgical patients with bone marrow depression ?

A

Infection

26
Q

What Aldehyde that is a good disinfectant ?

A

Glutaraldehyde

27
Q

T/F
Vertical transmission is an example of transmitting disease from mom to baby ?

A

True

28
Q

T/F
Phosphodiesterase inhibitors are not used to treat HIV ?

A

True

29
Q

All of these are ways HIV is transmitted except what?
a. urine
b. blood
c. semen
d. breast milk

A

a. urine

30
Q

T/F
Clavulanic acid is used w/Amoxicillin in Augmentin to slow the rate of renal secretion of Amoxicillin.

A

False

31
Q

T/F
Ampicillin is the drug of choice to treat infections due to Pseudomonas aeruginosa?

A

False
Ciprofloxacin is drug of choice for P aer

32
Q

Which of the following antibiotics is considered to possess the greatest level of neuromuscular blockade?

A

Telithromycin (Ketek)
Black box warning with Myasthenia Gravis patients

33
Q

T/F
Pseudomembranous colitis is caused by a bacterial toxin and is best treated with Clindamycin (Cleocin) ?

A

False C-dif best treated with oral Vanco

34
Q

Which of the following compounds is not used as an antiseptic?

A

Ethylene Oxide (Its a disinfectant)

35
Q

T/F
Ribavirin (Virazole) has been shown to shorten the duration of viral pneumonia infections ?

A

True

36
Q

T/F
Cyclophosphamide (Cytoxan) acts to kill cancer cells by substituting for purines in DNA synthesis ?

A

False

37
Q

T/F
Highly active antiretroviral therapy (HAART) is a therapeutic method primarily used to treat various body cancers ?

A

False, it treats HIV

38
Q

T/F
A sarcoma is a cancer of cells in the bloodstream ?

A

False

39
Q

T/F
Most antiseptics act by altering the structure &/or function of the bacterial cell wall ?

A

True

40
Q

T/F
The varicella-zoster virus is responsible for causing shingles ?

A

True

41
Q

T/F
Genital herpes (type II) can be cured by a five day regimen of Valacyclovir (Valtrex) therapy ?

A

False
NO CURE, helps treat pain

42
Q

Which of the following enzymes converts single stranded RNA into DNA ?

A

Reverse Transcriptase

43
Q

Which of the following virus’ is believed to cause Burkitt’s lymphoma?

A

None of these answers are correct
It is caused by Epstein-Barr virus

44
Q

T/F
Isopropyl alcohol is ineffective as an antiseptic against most viral organisms.

A

True
It kills bacteria, NOT virus’ or fungal

45
Q

T/F
Methotrexate is an analog of folic acid?

A

True

46
Q

T/F
Bone marrow depression is a common DLT in anticancer therapy ?

A

True

47
Q

T/F
Care should be taken during GA in pts who have been taking Busulfan (Myleran) due to an enhanced risk of pulmonary complications ?

A

True

48
Q

T/F
HIV reverse transcriptase acts to insert the viral DNA into the host cell DNA ?

A

False

49
Q

What is the main difference between Amantadine and Rimantadine ?

A

Hepatic metabolism- Rimantadine

50
Q

Which antibiotic has Gray baby syndrome adverse effect?

A

Chloramphenicol

51
Q

What is over the counter medication to treat UTI painful symptoms for women?

A

Phenazopyridine

52
Q

How many days does it take for HIV antibodies to show up in a lab test?

A

25 days

53
Q

What is a new aminioglycoside for treating complicated UTIs?

A

Plazomicin