Pathopharm 2 Exam 3 Flashcards

1
Q

Which causes mycosis?

A

Fungi

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2
Q

T/F
Pandemic is across a continent?

A

True

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3
Q

T/F
Shingles disorder is caused by the reactivation of herpes virus?

A

True

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4
Q

T/F
The primary advantage of Rimantadine (Flumadine) over Amantadine (Symmetrel) is the greatly increased spectrum of antiviral activity ?

A

False
Rimantadine advantage is hepatic metabolism that avoids toxicity

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5
Q

T/F
Peramivir is used as flu prophylaxis?

A

False
Not prophylaxis, but decreases length of infection

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6
Q

HIV attacks which cell?

A

CD4+ T cells

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7
Q

T/F
Remdesivir is a protease inhibitor used to treat HIV ?

A

False
Treats COVID-19

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8
Q

T/F
Cyclophosphamide is a purine analog used to inhibit DNA synthesis ?

A

False
Its an alkylator used to cross-link DNA

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9
Q

T/F
5-Fluorouracil is a purine analog ?

A

False
It an analog of uracil

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10
Q

T/F
Bleomycin causes SIADH secretion ?

A

False
only Cyclophosphamide and Vincristine do

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11
Q

Which one of these has a half-life of 10 days?
a. none of these
b. linezolid
c. vancomyocin

A

None of the these

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12
Q

Paclitaxel, Docetaxel, and Carbazitael do all of the following except ?

A

Hepatic toxicity

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13
Q

T/F
Carboplatin has a longer half-life than Cisplatin ?

A

True

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14
Q

Which one of these is an iron source and enters cell?

A

Cefiderocol

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15
Q

T/F
(IA) should be avoided in cancer patients due to immunosuppression?

A

True

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16
Q

What is the drug of choice for Bordetella (whooping cough) ?

A

macrolides- erythromycin, clarithromycin, azithromycin

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17
Q

Which one of these is not a beta-lactam?
a. clarithromycin
b. vancomycin
c. cephalosporin
d. none of these

A

a. clarithromycin (macrolide)

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18
Q

T/F
Kernicterus is caused by bilirubin buildup?

A

True

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19
Q

T/F
The sulfonamide antibiotics are analogs of para-amino-benzoic-acid (PABA) ?

A

True

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20
Q

The flu is a?
1. virus
2. bacteria
3. fungi

A

Virus

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21
Q

T/F
OU abbreviation is both ears ?

A

False
Its both eyes

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22
Q

T/F
Legend drugs do not need a prescription for outpatient therapy, and only signature from the patient ?

A

False
Legend = Controlled substances

23
Q

T/F
Ceftriaxone (Rocephin) is the drug of choice for gonorrhea infections ?

24
Q

T/F
Glucose control decreases infection?

25
What is a risk in surgical patients with bone marrow depression ?
Infection
26
What Aldehyde that is a good disinfectant ?
Glutaraldehyde
27
T/F Vertical transmission is an example of transmitting disease from mom to baby ?
True
28
T/F Phosphodiesterase inhibitors are not used to treat HIV ?
True
29
All of these are ways HIV is transmitted except what? a. urine b. blood c. semen d. breast milk
a. urine
30
T/F Clavulanic acid is used w/Amoxicillin in Augmentin to slow the rate of renal secretion of Amoxicillin.
False
31
T/F Ampicillin is the drug of choice to treat infections due to Pseudomonas aeruginosa?
False Ciprofloxacin is drug of choice for P aer
32
Which of the following antibiotics is considered to possess the greatest level of neuromuscular blockade?
Telithromycin (Ketek) Black box warning with Myasthenia Gravis patients
33
T/F Pseudomembranous colitis is caused by a bacterial toxin and is best treated with Clindamycin (Cleocin) ?
False C-dif best treated with oral Vanco
34
Which of the following compounds is not used as an antiseptic?
Ethylene Oxide (Its a disinfectant)
35
T/F Ribavirin (Virazole) has been shown to shorten the duration of viral pneumonia infections ?
True
36
T/F Cyclophosphamide (Cytoxan) acts to kill cancer cells by substituting for purines in DNA synthesis ?
False
37
T/F Highly active antiretroviral therapy (HAART) is a therapeutic method primarily used to treat various body cancers ?
False, it treats HIV
38
T/F A sarcoma is a cancer of cells in the bloodstream ?
False
39
T/F Most antiseptics act by altering the structure &/or function of the bacterial cell wall ?
True
40
T/F The varicella-zoster virus is responsible for causing shingles ?
True
41
T/F Genital herpes (type II) can be cured by a five day regimen of Valacyclovir (Valtrex) therapy ?
False NO CURE, helps treat pain
42
Which of the following enzymes converts single stranded RNA into DNA ?
Reverse Transcriptase
43
Which of the following virus' is believed to cause Burkitt's lymphoma?
None of these answers are correct It is caused by Epstein-Barr virus
44
T/F Isopropyl alcohol is ineffective as an antiseptic against most viral organisms.
True It kills bacteria, NOT virus' or fungal
45
T/F Methotrexate is an analog of folic acid?
True
46
T/F Bone marrow depression is a common DLT in anticancer therapy ?
True
47
T/F Care should be taken during GA in pts who have been taking Busulfan (Myleran) due to an enhanced risk of pulmonary complications ?
True
48
T/F HIV reverse transcriptase acts to insert the viral DNA into the host cell DNA ?
False
49
What is the main difference between Amantadine and Rimantadine ?
Hepatic metabolism- Rimantadine
50
Which antibiotic has Gray baby syndrome adverse effect?
Chloramphenicol
51
What is over the counter medication to treat UTI painful symptoms for women?
Phenazopyridine
52
How many days does it take for HIV antibodies to show up in a lab test?
25 days
53
What is a new aminioglycoside for treating complicated UTIs?
Plazomicin