Pathopharm 2 Exam 2- S5

Question 1

T/F
Bleeds are more common in the antrum of the stomach and not the fundus of the stomach ?

Answer 1

True

Question 2

Too much sodium bicarb or antacid can cause?

Answer 2

Systemic Alkalosis

Question 3

Which Adenosine Diphosphate (ADP) inhibitor is not a prodrug?

Answer 3

Cangrelor (Kengreal)

Question 4

Amiloride (Midamor) works where?

Answer 4

Late distal convoluting tubule and collecting ducts

Question 5

Hematopoiesis occurs in what during fetal life?

Answer 5

Spleen

Question 6

Heparin activity is due to what?

Answer 6

Pentasacchrides structure

Question 7

T/F
Nephrotic has more albumin and red blood cells than nephritic syndrome ?

Answer 7

True

Question 8

T/F
PGE2 inhibits proton pump?

Answer 8

True

Question 9

T/F
Kuppfer cells are part of the central innate immunity and are bactericidal?

Answer 9

True

Question 10

Which is bactericidal in urine as a part as the host defense mechanisms?
a. Glucose
b. Urea
c. None of these
d. Calcium

Answer 10

b. Urea

Question 11

T/F
Gemfibrozil causes rhabdomyolysis and should be stopped in periop period ?

Answer 11

True

Question 12

T/F
Statins should be stopped perioperatively ?

Answer 12

False

Question 13

T/F
Infants are born with 50% less of lymphocytes than children, but increase to adults levels as they grow, this is accounts for their viral colds ?

Answer 13

False

Question 14

T/F
Zollinger ellison is from too much pepsin leading to increased gastric acid secretion?

Answer 14

False
its from too much grastin

Question 15

Which diuretic works at the ascending loop of Henle?

Answer 15

Bumetanide
It is a “high ceiling” Loop diuretic

Question 16

What is the primary cause of ulcers?

Answer 16

None of these answers
H. pylori

Question 17

T/F
Hemophilia A is from factor VIII deficiency?

Answer 17

True

Question 18

T/F
Vitamin K is a fat-soluble vitamin?

Answer 18

True

Question 19

What does Plasmin do?

Answer 19

Breaks down fibrin

Question 20

Heparin achieves hemostasis via?

Answer 20

Inhibits thrombin activity with antithrombin III activity

Question 21

T/F
Heparin is a penta-amine acid?

Answer 21

False its a pentasaccharide

Question 22

Treatment of choice for pernicious anemia?

Answer 22

Vitamin B12 injection

Question 23

Lactose deficiency leads to what?

Answer 23

Osmotic diarrhea

Question 24

Deposition of bilirubin in the brain?

Answer 24

Kernicterus

Question 25

Heparin works on which coagulants?

Answer 25

IXa, Xa, XIa,XIIa

Question 26

Which condition produces augmented clot formation and accelerated fibrinolysis?

Answer 26

DIC

Question 27

Which one of these is associated with headache dose related?

Answer 27

Niacin

Question 28

Which is not synthesized by the liver?

Answer 28

Chylomicrons

Question 29

T/F Omeprazole inhibits the NA/K ATPase pump?

Answer 29

False, it inhibits Na/H ATPase

Question 30

Which one is associated with ulcers from a burn injury?

Answer 30

Curlings

Question 31

T/F Celiac disease pancreatic enzyme?

Answer 31

False, It is an autoimmune intestinal reaction to gluten

Question 32

T/F Heparin is a protamine protein?

Answer 32

False, it is an glycoaminoglycan

Question 33

T/F Fibrates have been shown to possess a higher risk of rhabdomyolysis than the statins and should be discontinued prior to surgery?

Answer 33

True

Question 34

T/F Urine formation and excretion begin by the third month of gestation?

Answer 34

True

Question 35

What is potter syndrome?

Answer 35

Born without both kidneys

Question 36

Wilm’s tumor?

Answer 36

Embryonal tumor of kidney Birth-5 years of age Nephroblastoma Most common solid tumor of childhood Genes WT1 and WT2 on chromosome 11 Surgical exploration and resection

Question 37

T/F Staghorn calculi are large stones in the bladder?

Answer 37

False, they are kidney stones

Question 38

Which has decreased risk of viral transmission?

Answer 38

Plasma protein fraction

Question 39

T/F Hirschprung disease is a functional obstruction of the colon caused by an absence of the enteric ganglia?

Answer 39

True, also called congential aganglionic megacolon