Pathopharm 2 Exam 2- S5 Flashcards
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Bleeds are more common in the antrum of the stomach and not the fundus of the stomach ?
True
Too much sodium bicarb or antacid can cause?
Systemic Alkalosis
Which Adenosine Diphosphate (ADP) inhibitor is not a prodrug?
Cangrelor (Kengreal)
Amiloride (Midamor) works where?
Late distal convoluting tubule and collecting ducts
Hematopoiesis occurs in what during fetal life?
Spleen
Heparin activity is due to what?
Pentasacchrides structure
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Nephrotic has more albumin and red blood cells than nephritic syndrome ?
True
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PGE2 inhibits proton pump?
True
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Kuppfer cells are part of the central innate immunity and are bactericidal?
True
Which is bactericidal in urine as a part as the host defense mechanisms?
a. Glucose
b. Urea
c. None of these
d. Calcium
b. Urea
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Gemfibrozil causes rhabdomyolysis and should be stopped in periop period ?
True
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Statins should be stopped perioperatively ?
False
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Infants are born with 50% less of lymphocytes than children, but increase to adults levels as they grow, this is accounts for their viral colds ?
False
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Zollinger ellison is from too much pepsin leading to increased gastric acid secretion?
False
its from too much grastin
Which diuretic works at the ascending loop of Henle?
Bumetanide
It is a “high ceiling” Loop diuretic
What is the primary cause of ulcers?
None of these answers
H. pylori
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Hemophilia A is from factor VIII deficiency?
True
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Vitamin K is a fat-soluble vitamin?
True
What does Plasmin do?
Breaks down fibrin
Heparin achieves hemostasis via?
Inhibits thrombin activity with antithrombin III activity
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Heparin is a penta-amine acid?
False its a pentasaccharide
Treatment of choice for pernicious anemia?
Vitamin B12 injection
Lactose deficiency leads to what?
Osmotic diarrhea
Deposition of bilirubin in the brain?
Kernicterus
Heparin works on which coagulants?
IXa, Xa, XIa,XIIa
Which condition produces augmented clot formation and accelerated fibrinolysis?
DIC
Which one of these is associated with headache dose related?
Niacin
Which is not synthesized by the liver?
Chylomicrons
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Omeprazole inhibits the NA/K ATPase pump?
False,
it inhibits Na/H ATPase
Which one is associated with ulcers from a burn injury?
Curlings
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Celiac disease pancreatic enzyme?
False,
It is an autoimmune intestinal reaction to gluten
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Heparin is a protamine protein?
False, it is an glycoaminoglycan
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Fibrates have been shown to possess a higher risk of rhabdomyolysis than the statins and should be discontinued prior to surgery?
True
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Urine formation and excretion begin by the third month of gestation?
True
What is potter syndrome?
Born without both kidneys
Wilm’s tumor?
Embryonal tumor of kidney
Birth-5 years of age
Nephroblastoma
Most common solid tumor of childhood
Genes WT1 and WT2 on chromosome 11
Surgical exploration and resection
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Staghorn calculi are large stones in the bladder?
False,
they are kidney stones
Which has decreased risk of viral transmission?
Plasma protein fraction
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Hirschprung disease is a functional obstruction of the colon caused by an absence of the enteric ganglia?
True, also called congential aganglionic megacolon
