Pathology of the Pituitary GLand

Question 1

Anatomically, where does the pituitary gland lie?

Answer 1

In the Sella Turcica between the anterior and posterior clinoid processes

Question 2

Infarction of the Pituitary generally involves what part?

Answer 2

The anterior lobe due to vascular supply

Question 3

About what percentage of the lobe must be lost for symptoms to occur

Answer 3

75%

Question 4

Causes of infarction in the anterior pituitary

Answer 4

• Diabetes Mellitus
• Cranial Vascular Atrophy
• Increased intracranial pressure
• Hypoperfusion
• Sheehan’s syndrome
• Pituitary apoplexy

Question 5

Inflammatory lesions of the pituitary caused by

Answer 5

Acute inflammation (sinusitis, osteomyelitis)
Granulomatous (TB, fungal, sarcoid, Giant Cell)
Lymphocytic (autoimmune)

Question 6

Addison’s disease

Answer 6

ACTH hyperplasia is one feature

Question 7

Pituitary adenomas are the most important thing in the lecture

Answer 7

ok

Question 8

Pituitary adenomas are what percent of intracranial neoplasms

Answer 8

10%

Question 9

age range of pituitary neoplasms

Answer 9

30-50

Question 10

Pituitary adenomas are generally isolated

Answer 10

true

Question 11

Pituitary adenoma gross morphology

Answer 11

Typically fragmented due to standard transsphenoidal surgical approach. Well circumscribed

Question 12

Histology of pituitary adenoma

Answer 12

sheet like growth pattern

loss of reticulin fiber network