Hormones table Flashcards

1
Q

What does the Hypothalamus secrete?

A
  • Releasing hormones: TRH, GnRH, CRH, GHRH,

- Inhibiting hormones: Somatostatin, PIH (Prolactin inhibitory hormone…also called dopamine.

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2
Q

What is the chemical nature of all things released by the hypothalamus?

A

All peptides except for PIH (amine)

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3
Q

Major stimuli for secretion

A

blank

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4
Q

What is released by the posterior pituitary gland?

A

Oxytocin and Vasopressin

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5
Q

Function of oxytocin

A

Let down breast milk by increasing the contractility of the myoepithelial cells, Uterine smooth muscle contraction

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6
Q

Function of vasopressin

A

Decrease water excretion, (aquaporins)

Increase contractility of smooth muscle which increases blood pressure

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7
Q

Major stimuli for vasopressin release?

A

Low plasma volume or high plasma osmlarity

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8
Q

What are the major hormones released by the Anterior Pituitary gland

A
Growth Hormone
Adrenocorticotrophic  hormone
Thyroid Stimulating Hormone
Leutenizing hormone
Prolactin
Follicle Stimulating hormone
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9
Q

Growth hormone is responsible for what?

A
  • Growth, organic metabolism; secretion of somatomedin by liver and cartilage
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10
Q

Thyroid Stimulating Hormone does what?

A

Stimulates synthesis and secretion of thyroid hormones. Increases size of the thyroid gland.

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11
Q

Adrenocorticotrophic hormone does what?

A

Adrenal cortex (mainly increases in cortisol. Some increase in androgens and aldosterone)

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12
Q

Prolactin does

A

Increases milk synthesis in the breasts, also stimulates breast development and inhibits ovulation

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13
Q

Leutenizing hormone does what

A

Stimulates testosterone synthesis on Leydig cells of the testes.
Stimulates ovulation, formation of the corpus luteum, estrogen and progesterone synthesis in ovaries

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14
Q

Follicle stimulating Hormone does qhat

A

Sperm maturation in the testis, follicular development and estrogen in the ovaries.

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15
Q

Which cell types in the anterior pituitary are classified as basophils

A

Everything except GH and PRL

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16
Q

GH and PRL are

A

Acidophils

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17
Q

What hormones are released by the adrenal cortex?

A
Cortisol
Adrenal Androgens (DHEA and adrostenedione)
Aldosterone
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18
Q

All of the hormones released by the adrenal cortex are of what chemical nature?

A

Steroids

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19
Q

Cortisol does what?

A

Stimulates gluconeogenesis; inhibits inflammatory response, suppresses immune response, enhances vascular response to catecholamines

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20
Q

Aldosterone does what

A

increases Na reabsorption in the kidneys, increases K secretion, inc H secretion

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21
Q

Adrenal androgens do what?

A

stimulate spermatogenesis and male secondary sex characteristics.

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22
Q

Just gonna do some actions for a while

A

ok

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23
Q

What hormones does the Endocrine Pancreas secrete?

A

Insulin

Glucagon

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24
Q

What is the main function of insulin?

Glucagon?

A

insulin decreases blood glucose

glucagon increases blood glucose

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25
What hormones are secreted by the placenta?
- Human Chorionic Gonadotropin (hCG) - Human Placental Lactogen (HPL) or human chorionic sommatotropin - Estriol - Progesterone
26
What does HCG do?
Stimulates Estrogen and Progesteronesynthesis in the corpus luteum of early pregnancy
27
What does HPL do?
Growth like and Prolactin like actions during pregnancy
28
What does Estradiol do?
stimulates growth and development of female repro system, follicular phase of menstrual cycle, development of breasts, prolactin; maintians pregnancy
29
What does Prgesterone do?
Stimulates the Luteal phase of the Menstrual cycle
30
What hormones are produced by the ovaries?
Estradiol and Progesterone
31
What hormones are produced by the Testis
Testosterone
32
Action of testosterone
stimulates secondary sex characteristics in the make, stimulates spermatogenesis
33
Adrenal cortex hormones?
Aldosterone Cortisol DHEA androstenedione
34
ALdosterone does what?
increases renal Na absorption, K secretion, H secretion
35
Cortisol does what
stimulates gluconeogenesis, inhibits inflammation, | suppresses immune response, enhances vascular response to catecholamines
36
Tits getting bigger (branching of mammary ducts) is accomplished by what three hormones?
Prolactin, Estrogen, Progesterone Add some PEP to her step.
37
During pregnancy, what three hormones contribute to enlargement of the mammary alveoli
Prolactin, Estrogen, Progesterone again
38
Major action of prolactin?
Inducing transcroption of the genes for milk production
39
Why do breasts not secrete milk during pregnancy? | Milk production only occurs after the birth of the child
Because Estrogen and Progesterone levels are very high and they down-regulate the number of Prolactin receptors. At birth though, Estrogen and Progesterone levels fall rapidly and Prolactin is free to bind so milk production begins
40
How does Prolactin prevent ovulation
inhibits synthesis and release of GnRH. This means that fertility is greatly reduced during breast feeding. Also means that males with a prolactinoma (the most common pituitary adenoma, will have infertility.
41
Prolactin secretion is inhibited by
Dopamine
42
What does T3 do to GH levels?
Increases it
43
What 2 hormones are needed for spermatogenesis?
Testosterone and FSH.... | Really requires 3 because you have to have LH for testosterone
44
Inhibin does what and is made where
reduces FSH, sertoli cells
45
Testosterone feeds back and inhibits LH
truth
46
Testosterone also inhibits GnRH
truth
47
Estrogen is a type of estradiol
ok
48
Low Estrogen does what to FSH and LH
Inhibits it
49
High E
High LH and FSH. Leads to mid-cycle LH surge that causes ovulation
50
Very high E
inhibitory, used to be used as birth control
51
Very Low E + progesterone
Now used in BC
52
Does estrogen have an effect on female body configureation
yes....widening of hips, fat content and distribution
53
Estrogen's effects on the oviducts: Uterus: Cervical mucous
Oviducts: Grwoth of muscle and epithelium, motility, ciliary beating Uterus: growth of myometrium, increased contractility, growth of endometrium, development of spiral arteries and blood supply
54
Progesterone's effect on uterine muscle
antagonizes estrogen...decreases contractions partly by downregulating the number of estrogen receptors
55
Lets talk about the actions of Cortisol
ok
56
Overall, the metabolic effects of cortisol can be described with two words, they are
Catabolic and diabetogenic....Increases glucose synthesis - Increases protein catabolism and decreases new muscle synthesis in order to provide new amino acids to the liver. - lipolysis which provides glycerol to the liver for gluconeogenesis - decreases glucose utilization bu tissues - decreases insulin sensitivity in adipose tissue. SO, in keeping with the adrenal as a stress gland, cortisol makes sense because it keeps blood glucose high during fasting.
57
Hypercortisolism (Cushing's) leads to what effect onb blood sugar
hyperglycemia
58
Low Cortisol (addison's dz) leads to what effect?
hypoglycemia
59
Cortisol and inflammation
Anti-inflammatory: - No precursors to prastaglandins or leukotrienes - No IL-2 so no T cell prolif - Inhibits histamine and serotonin
60
Immune response and Cortisol
SUppressed
61
Cortisol and blood pressure
Necessary for normal blood pressure. Upregulates alpha 1 receptors in arterioles. This makes it required for vasoconstriction
62
Hypocortisolism and blood pressure
hypotensive
63
Hypercortisolism and bp
hypertensive (cushings(
64
Bone formation and Cortisol?
inhibited....no type 1 collagen
65
Sleep
Increases awake time
66
What affect does thyroid have on GH
Increases GH synthesis
67
PTH encourages the kidneys to do what
Resob calcium and expell phosphate
68
PTH encourages bones to do what
mobilize calcium....remember our biggest storage area of calcium is the bone
69
Excessive intake of Vitamin D and ionized calcium
VIT D intoxication can lead to low calcium levels
70
Structure of ACTH
small single chain peptide hormone with no subunits
71
The only amine hormones are
dopamine, the two thyroids, and catecholamines
72
THYROID GOES UP DURING PREGNANCY WHY?
Increased thyroid binding lgobulins
73
Peptides are broken down by the GI tract and never reach the circulation
Amines and Steroids are succewsfully absorbed
74
What the fuck does Inhibin do in males?
STOPS FSH SECRETION from teh sertoli cells of the testis which decreases spermatogenesis. Fsh...Fucking...Sperm.
75
Growth, motility, and SECRTIONS of oviduct, uterus , and vagina
EStrogen