Path 3 Esophagus Flashcards

1
Q

Esophagus lining

A

Non-keratinized stratified squamous

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2
Q

Most common congenital anomaly

A
  • Tracheoesophageal Fistulas

- Commonly with atresia

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3
Q

Scleroderma

A
  • Autoimmune disease

- Systemically affects Esophagus, Kidneys, Heart, and Lungs

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4
Q

Zenker diverticulum

A
  • Pharyngoesophageal diverticulum

- Immediately above upper esophageal sphincter

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5
Q

Traction diverticulum

A

Mid esophagus

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6
Q

Epiphrenic diverticulum

A

Right above diaphragm

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7
Q

Plummer-Vinson syndrome

A
  • Iron deficiency anemia
  • Esophageal web
  • Atrophic glossitis (beefy red tongue)
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8
Q

Esophageal Webs

A
  • Women >40

- Increased risk for SQC

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9
Q

Mallory-Weiss Tear

A
  • Laceration at gastroesophageal junction
  • Caused by wretched vomiting
  • High risk of transmural rupture
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10
Q

Boerhaave syndrome

A

Esophageal rupture -> air in mediastinum, subcutaneous emphysema

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11
Q

Esophageal Varices

A

-Increased portal pressure

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12
Q

Odynophagia

A

Pain on swallowing

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13
Q

Nutcracker Esophagus

A
  • Excessively strong contractions
  • Associated with GERD (Tx same)
  • Outer longitudinal contracts independently from inner circular
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14
Q

Diffuse Esophageal Spasms

A

-Diffuse uncoordinated peristalsis

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15
Q

Achalasia

A
  • Absence of peristalsis and failure of LES relaxation

- Due to myenteric ganglion cell damage

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16
Q

Achalasia secondary causes

A
  • Chagas disease (Trypanosoma cruzi)

- Infiltrative malignancy, amyloidosis, sarcoidosis, scleroderma

17
Q

Achalasia xray appearance

A

Bird-beak sign on barium swallow

18
Q

Chagas Disease

A
  • T. cruzi

- Destruction of autonomic nervous system in GI and Heart

19
Q

CMV v Herpes histology

A

Cytoplasmic v Nuclear inclusions

20
Q

Most common esophagitis

A

Reflux esophagitis due to absent LES tone

21
Q

GERD histology

A

Intraepithelial eosinophils and neutrophils

22
Q

GERD Tx

A

PPI, H2-R antagonists

23
Q

Barrett esophagus change

A

Squamous -> columnar, goblet

intestinal metaplasia

24
Q

Adenocarcinoma

A
  • Lower 1/3 of esophagus
  • From GERD
  • Caucasian men
25
Q

Squamous Cell Carcinoma

A
  • Upper or middle 1/3 of esophagus
  • From alcohol, tobacco, Achalasia, Esophageal Web, chemical injury
  • African American men
26
Q

Esophageal cancer with hoarseness and cough

A

Squamous Cell Carcinoma