Path 1 Oral Cavity Flashcards

1
Q

Aphthous Ulcer associations (3)

A
  • Behcets disease
  • Inflammatory bowel disease
  • Celiac disease
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2
Q

Herpes Dx

A

Intranuclear inclusions and multinucleated polykaryons

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3
Q

Thrush

A
  • Candida Albicans
  • Immunosuppressed patients
  • Pseudohyphae
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4
Q

Fibroma

A
  • Chronic irritative lesion

- Dense connective tissue hyperplasia

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5
Q

Pyogenic Granuloma

A
  • Lobular Capillary Hemangioma

- Epidermal collarette

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6
Q

Leukoplakia

A

-5-25% premalignant

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7
Q

Erythroplakia

A
  • 50% premalignant
  • Carcinoma in situ
  • Thickened mucosal hyperplasia
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8
Q

Most common oral cancer

A
  • 95% Squamous cell carcinoma

- Frequent field effect

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9
Q

SQC pathogenesis (2 pathways)

A
  1. Alcohol, Betelnut, Tobacco (mutated p53, NOTCH 1)

2. HPV-16 (tonsillar crypts, base of tongue)

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10
Q

Xerostomia

A
  • Dry mouth
  • Associated with anticholinergics, radiation, analgesics, antihitamines
  • Atrophy of taste papillae
  • Sjogrens syndrome
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11
Q

Sialadenitis

A
  • Inflammation of salivary gland
  • Viral - Mumps (paramyxovirus)
  • Bacterial - Staph
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12
Q

Sialolithiasis

A
  • Salivary duct obstruction

- Predisposes to bacterial infection

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13
Q

Mucocele

A
  • Cyst filled with mucin & inflammatory cells

- Lined by granulation, not epithelium

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14
Q

Pleomorphic Adenoma

A
  • Benign salivary stromal tumor

- High rate of recurrence if incompletely excised

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15
Q

Warthin tumor

A
  • Benign cystic parotid tumor
  • Lymph node-like stroma
  • Distinct histology
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16
Q

Adenoid cystic tumor

A
  • Submandibular gland

- Perineural spread makes resection challenging

17
Q

Mucoepidermoid carcinoma

A
  • Malignant mucinous/squamous salivary tumor

- Frequently involves facial nerve (parotid)

18
Q

Dentigerous cyst

A

-Cyst around crown of unerupted tooth

19
Q

Odontogenic keratocyst

A
  • Aggressive posterior mandible tumor

- Gorlins syndrome -> multiple lesions

20
Q

Gorlins syndrome

A
  • Nevoid Basal Cell Carcinoma Syndrome

- Odontogenic keratocysts

21
Q

Periapical cyst

A

Inflammatory cyst following pulp infection

22
Q

Ameloblastoma

A

From odontogenic epithelium

23
Q

Odontoma

A

Shows deposition of enamel and dentin