Micro 3 Normal Flora Flashcards
1
Q
Metagenomics
A
Genomic study of uncultured microorganisms (shotgun sequencing)
2
Q
Biggest demographic GI flora difference
A
Infant v. Adult
3
Q
Diverse v Conserved (between subjects)
A
Species v Metabolic Pathways
4
Q
Gut bacteria roles
A
Mostly anaerobic, little enteric
5
Q
Gut immunity
A
Dendritic cells in LP of Peyer’s Patches sense bacteria -> Lymph nodes respond with IgA
6
Q
Epithelial cell secretion against bacterial TLR binding
A
Reg III gamma, & alpha-defensins
7
Q
Important defense against penetrating bacteria
A
Th17
8
Q
Reduced normal flora predisposes to what bacterial infection
A
Clostridia Difficile
9
Q
Normal C. Diff Tx
A
Vancomycin
