Micro 7 H. Pylori Flashcards
1
Q
Helicobacter pylori micro
A
G- spiral (like campylobacter)
-urease
2
Q
H.pylori cancer risk
A
- Gastric carcinoma
- Gastric B-cell lymphoma
3
Q
H.pylori pathogenesis
A
- Penetrate mucus with spiral flagella
- Kill cells with cytotoxin and ammonia (via urease)
4
Q
H.pylori virulence (4)
A
- Flagella
- Adhesins
- Urease
- Cytotoxin
5
Q
H.pylori Dx
A
Urease breath test
Biopsy
6
Q
H.pylori Tx
A
- PPI
- Bismuth
- Amoxicillin and Clarithromycin
7
Q
Listeria monocytogenes micro
A
G+ coccobacillus on short chains
- B hemolytic
- Blue-green colonies on oblique light
- Grow and replicate at 4 degrees
8
Q
Listeria transmission
A
- Cold cuts and hot dogs
- Childbirth
- Soil, water, animals
9
Q
Listeria neonatal disease
A
- Granulomatosis infantiseptica (in utero infection of fetus, very dangerous)
- Meningitis & sepsis (birth exposure)
10
Q
Listeria adult disease
A
- Febrile noninflammatory gastroenteritis (Pregnant, immunocompromised, elderly)
- Meningitis (Cancer, renal transplant pt)
- Bacteremia
11
Q
Listeria virulence
A
Listeriolysin O and phospholipases
-Disrupt phagocytic vacuole, recruit actin to get into adjacent macrophage
12
Q
Listeria Dx
A
Culture, NOT gram stain
13
Q
Listeria Tx
A
Ampicillin
+Gentamicin for meningitis
14
Q
Esophageal infections
-Thrush, vesicles, multi-system
A
- Candida
- HSV
- CMV
15
Q
Trypanosoma cruzi (chagas) infection
A
- Megaesophagus or megacolon (neuron loss)
- Bolivia
