Passmed immunology Flashcards
Type II hyper
IgG or IgM (cell surface)
Type 3 hyper
Free antigen and antibody combine (IgG, IgA)
Cytokine for chemotaxis of neutrophils
IL8
Cytokine to stimulate growth of T cells
IL 2 from Th1 cells
Cytokine to sitmulate growth of B cells
IL4 from Th2 cells
Actives NK cells and stimulates differentiation of naive T cells to Th1 cells
IL12 from macrophages, dendritic and B cells
Activates macropahges
Interferon-y from Th1 cells
Best antibody for activated compliment cascade
IgM
Function Th1 and Th2
1 - cell mediated response and type 4 hypersensitivity
2 - humeral (antibody) immunity, production of antibodies
Ig in breast milk
IgA
Ig that can cross placenta
IgG
Most common Ig
IgA
But IgG in serum as most A on mucosal surfaces
AntiA/B is
IgM
First antibody secreted
IgM