Haematology - Microcytic Flashcards
Fe dificiency sy
Sore red tongue, koilonychia
Fe deficiency ax
Blood loss or malabsorption
Iron deficiency mx
Oral ferrous sulphate
Normal haem genes
2a2b
Alpha thalassamie mx
Blood transfusion
Bone marrow transplant can be curative
(single gene effected, both genes is called hydrops fetalis and incompatible with life)
Beta minor px
Carrier (1 abnormal, 1 normal)
Beta minor sy
Microcytic anaemia
Beta minor mx
None
Beta intermediate px
2 defective (or 1 defective, 1 deleted)
Beta intermedia mx
Blood transfusion
beta major px
Two deletions
Beta major sy
Severe anaemia and failure to thrive
Thalassaemia sy
Anaemia, splenomegaly
Sickle cell sy
Bone pain, jaundice, failure to thrive
Sickle cell crises precipitation
Infection, dehydration, hypoxia, cold