Passage Of Drugs Across Cell Membrane Flashcards
1
Q
How does the cell membrane allow for passage of water-soluble drugs ?
A
Cell membrane contains minute pores
2
Q
All pharmacokinetic processes involve what
A
Transport of the drug across biological membranes
3
Q
Degree of ionization depends on what
A
PKa of the drug
PH of the membrane
4
Q
Weak acid and weak base are better absorbed in what ?
A
5
Q
Toxicity with acidic drugs could be treated by what ?
A
Alkalization of urine
6
Q
Toxicity with basic drugs could be treated with what ?
A
Acidification
7
Q
What is meant by ion trapping in breast milk ?
A
8
Q
Drugs are transported across the membrane by what
A
