Non Steroidal Anti-inflammatory Drugs (NSAIDs) Flashcards by Лили Ауси | Brainscape

Q

What is the pharmacokinetics of NSAIDs

A

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Q

Name a non selective COX inhibitor

A

Aspirin

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Q

Explain the chemistry and pharmacokinetics of acetylsalicylic acid

A

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Q

What is the difference between aspirin and other NSAIDs

A

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Q

List the pharmacological effects of aspirin

A

Analgesic action
Antipyretic effect
Anti-inflammatory, anti-immunological and anti-rheumatic
Respiratory effects
CVS effects
GIT effects
Hepatic effects
Hematologist effects
Renal effects

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Q

Explain the analgesic action of aspirin

A

For mild to moderate intensity pain (not severe)

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Q

Explain the mechanism of analgesic action of aspirin

A

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Q

Explain the antipyretic effect of aspirin

A

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Q

Explain the mechanism of antipyretic effect of aspirin

A

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Q

Explain the mechanism of anti-inflammatory, anti-immunological and anti-rheumatic effect of aspirin

A

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Q

Explain the respiratory effect of aspirin

A

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Q

Explain the CVS effect of aspirin

A

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Q

Aspirin can produce what two types of gastric ulcers

A

Acute and chronic

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Q

Explain acute gastric ulcer and its pathogenesis

A

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Q

Explain chronic gastric ulcer and its pathogenesis

A

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Q

What are the two types of hepatic injury that aspirin can produce

A

Mild and severe hepatic injury

Q

Explain mild hepatic injury

A

Q

Explain the severe hepatic injury

A

Q

Explain hematologic effects of aspirin

A

Q

Explain the 3 renal effects caused by aspirin

A

Q

What are the therapeutic uses of aspirin

A

Q

What is the adverse effects of aspirin in GIT

A

Q

What is the adverse effect of aspirin on hepatic

A

Q

What is the adverse effect of aspirin on blood

A

Q

What is the adverse effect of aspirin on kidney

A

Q

What is the adverse effect of aspirin as hypersensitive reaction

A

Q

What are the precautions and contraindications of aspirin

A

Q

What are the characteristics of the selectivity COX-2 inhibitors

A

Q

What was taken off the market for potential cardiac effects

A

Rofecoxib