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Pharmacology > Cholinergic System > Flashcards

Cholinergic System Flashcards

1
Q

What is the fate of neurotransmitters

A
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2
Q

What are the two types of cholinesterase enzyme

A

True cholinesterase
Pseudo cholinesterase

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3
Q

What is the site of true cholinesterase

A

All cholinergic sites, motor end plate, RBCs and CNS

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4
Q

true cholinesterase is specific for what

A

For acetylcholine

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5
Q

What is the effect of deficiency of true cholinesterase

A

Fetal

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6
Q

What is the regeneration time of true cholinesterase

A

3-6 months

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7
Q

What is the site of pseudo cholinesterase

A

Present in liver and plasma

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8
Q

Pseudo cholinesterase is specific for what

A
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9
Q

What is the effect of pseudo cholinesterase in deficiency

A

Not fetal

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10
Q

What is the regeneration time of pseudo cholinesterase

A

2-3 weeks

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11
Q

What are the two classes of receptors for ACh

A
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12
Q

What are the types of muscarinic receptors

A

M1
M2
M3

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13
Q

Describe the M1

A
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14
Q

Describe the M2

A
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15
Q

Describe M3

A
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16
Q

What are the types of nicotinic receptors

A

Nm
Nn

17
Q

Describe Nm

A

Skeletal muscle - contraction

18
Q

Nn

A

Ganglia - CNS

19
Q

Muscarinic receptors are selectively stimulated and blocked by what

A

Stimulated - muscarine
Blocked - atropine

20
Q

Nm is blocked by what

A

Tubocurarine

21
Q

Nn is blocked by what

A

Hexamethonium

Pharmacology (25 decks)

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