Cholinergic System

Question 1

What is acetylcholine

Answer 1

Question 2

Where is Ach synthesized, stored and released from

Answer 2

Cholinergic neurons

Question 3

Explain synthesis, storage of Ach

Answer 3

Question 4

What is the fate of neurotra

Answer 4

Question 5

What are the two types of cholinesterase enzyme

Answer 5

True cholinesterase
Pseudo cholinesterase

Question 6

What is the site of true cholinesterase

Answer 6

All cholinergic sites, motor end plate, RBCs and CNS

Question 7

true cholinesterase is specific for what

Answer 7

For acetylcholine

Question 8

What is the effect of deficiency of true cholinesterase

Answer 8

Fetal

Question 9

What is the regeneration time of true cholinesterase

Answer 9

3-6 months

Question 10

What is the site of pseudo cholinesterase

Answer 10

Present in liver and plasma

Question 11

Pseudo cholinesterase is specific for what

Answer 11

Question 12

What is the effect of pseudo cholinesterase in deficiency

Answer 12

Not fetal

Question 13

What is the regeneration time of pseudo cholinesterase

Answer 13

2-3 weeks

Question 14

What are the two classes of receptors for ACh

Answer 14

Question 15

What are the types of muscarinic receptors

Answer 15

M1
M2
M3

Question 16

Describe the M1

Answer 16

Question 17

Describe the M2

Answer 17

Question 18

Describe M3

Answer 18

Question 19

What are the types of nicotinic receptors

Answer 19

Nm
Nn

Question 20

Describe Nn

Answer 20

Skeletal muscle - contraction

Question 21

Nn

Answer 21

Ganglia - CNS

Question 22

Muscarinic receptors are selectively stimulated and blocked by what

Answer 22

Stimulated - muscarine
Blocked - atropine

Question 23

What is the site of muscarinic receptors

Answer 23

Question 24

Nm is blocked by what

Answer 24

Tubocurarine

Question 25

Nn is blocked by what

Answer 25

Hexamethonium