Adrenergic System Flashcards

1
Q

What are the 3 closely related endogenous catecholamines in adrenergic system

A

Noradrenaline
Adrenaline
Dopamine

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2
Q

What is noradrenaline

A
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3
Q

What is adrenaline

A
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4
Q

What is dopamine

A
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5
Q

What are the two ways of termination of noradrenaline

A

Re-uptake
Metabolism

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6
Q

Explain re-uptake

A
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7
Q

What are the two ways metabolism can happen

A

Monoamine oxidase enzyme
Catechol-o-methyl transferase

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8
Q

What are the two types of MAO

A
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9
Q

Explain metabolism through MAO

A
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10
Q

Explain metabolism through catechol-o-methyl transferase (COMT)

A

Metabolizes NA in the synaptic space

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11
Q

The end product of catecholamine metabolism is what

A

Vanilyl mandelic acid

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12
Q

What is the normal urinary level of VMA

A
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13
Q

What are adrenergic receptors

A
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14
Q

What are the types of adrenergic receptors

A
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15
Q

Explain B1

A

Heart - increases cardiac properties
Kidney - renin
Increase in BP

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16
Q

Explain B2

A
17
Q

Explain B3

A

Fat converted to FA

18
Q

Explain alpha 1 and 2

A