PART 3 Flashcards
● Organisms that have been genetically engineered so that they carry one or more foreign genes from a different species
Transgenic Organisms
● Bigger challenge
More difficult to introduce foreign DNA into animal cells
○ Cloning more difficult
Transgenic animals
● More vitamins and better pest resistance
● Increase resistance to freezing
● Longer shelf life
● Increase vitamin A
● Edible vaccines
● Human proteins
● Increase resistance to pests
● Creates bigger leaves
○ Needed for photosynthesis
Transgenic Plants
● Introducing human genes into dairy animals in such a way that the human protein is produced in the dairy animal’s milk
Gene Pharming
● Introduction of human genes into human cells to treat or correct a disease
GENE THERAPY
● Human genes can be packaged and inject the genes
Retroviruses
○ An autosomal recessive
○ Inherited disorder
○ Highly susceptible to infection
○ Gene therapy
■ Attempt to introduce the gene for ADA into the patient’s T cell
Severe combined immunodeficiency (SCID)
○ Experimentally delivering the
“normal” gene in a viral vector to the recipients in a nasal spray
Cystic Fibrosis
○ Adds genes for interleukins into cancer cells
○ Cell death and checkpoints
Cancer
RNA cannot be used in
a PCR so the RNA needs to be DNA to be used
T OR F
TRUE
Purpose: to trigger a response for antibodies
VACCINES
■ Contains genetic
make-up of the virus or
bacteria
Genetic VACCINE
Live but weakened
■ Oral Polio vaccine
■ Codagenix
WEAKENED / ATTENUATED VACCINE
■ Kumuha ng protein sa
virus or bacteria
■ Novavax, Sanofi/GSK
■ Hepatitis B vaccine
Protein VACCINE
■ Patay na
■ Sinovax, Sinopharm, Bharat Biotech
■ Influenza vaccine
Inactivated VACCINE
