gene therapy and vectors transfer genes to humans Flashcards
involves manipulating certain genetic sequences, but its primary goal is not always to enhance physical traits or confer resistance. Instead, its main objective is to treat or correct specific diseases or disorders by targeting the underlying genetic causes or regulating symptoms.
GENE THERAPY
An inherited disorder, lack an enzyme, adenosine deaminase (ADA)
SCID (Severe Combined Immunodeficiency)
Deficiency of B and T cells
Highly susceptible to infections
SCID (Severe Combined Immunodeficiency)
is a condition where the body lacks the enzyme adenosine deaminase (ADA), a vital immune system enzyme
SCID (Severe Combined Immunodeficiency)
Is a condition characterized by the overaccumulation of mucus, leading to blockages in the airways
CYSTIC FIBROSIS
In —- treatment, gene therapy aims to modify interleukins within the patient’s genes. These interleukins regulate cell growth, helping to inhibit or regulate the overproduction of —- cells rather than directly killing them.
cancer
Human genes can be packaged in retroviruses, which can introduce genes into human cells
RETROVIRUSES
is used to amplify DNA, but COVID contains RNA instead. In this process, the RNA strand is converted into a DNA strand through a reversal process.
RT-PCR
contain the genetic material of COVID, which helps your body build immunity against the virus. This allows your body to remember the virus and respond more effectively if you encounter it again, potentially reducing the severity of the infection. The genetic material in these vaccines can be either DNA or RNA.
GENETIC VACCINES
contain the entire virus, but it’s been killed or inactivated before being used in the vaccine. This allows your body to recognize the virus and build immune memory against it, without causing illness.
INACTIVATED VACCINES
provide specific proteins from the virus to trigger an immune response without introducing the whole virus.
PROTEIN VACCINES
contain a weakened form of the virus that can still trigger an immune response but are not strong enough to cause illness.
ATTENUATED VACCINES