Parkinsons Case Drugs

Question 1

Levodopa

Answer 1

Levodopa crosses the blood-brain barrier, where it is then converted into dopamine by the enzyme aromatic L-amino acid decarboxylase (AAAD or DOPA decarboxylase). Dopamine itself cannot cross the blood-brain barrier, which is why its precursor, levodopa, is used.

Question 2

Co-beneldopa/co-careldopa

Answer 2

Question 3

Dopamine agonists

Answer 3

Question 4

Monoamine oxidase B inhibitors

Answer 4

Question 5

COMT inhibitors

Answer 5