Parasympathetic NS

Question 1

why are directly acting cholinomimetics more selective than indirectly acting cholinomimetics

Answer 1

they can be designed to stimulate either a muscarinic or nicotinic receptor.
indirectly acting drugs increase ACh regardless of the type of receptor

Question 2

how do indirectly acting cholinomimetic drugs act

Answer 2

block the breakdown of ACh

Question 3

how do directly acting cholinomimetic drugs act

Answer 3

bind to and stimulates muscarinic or nicotinic receptors

Question 4

how is anticholinesterase poisoning treated

Answer 4

IV antropine

help if in respiratory arrest

Question 5

what are the signs and symptoms of anticholinesterase poisoning

Answer 5

headache, nausea, dizziness, hypersecretion, twitch, muscle weakness