anti-psychotics Flashcards

1
Q

what are the main neurotransmitter defects in schizophrenia

A

too much dopamine

too little glutamate

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2
Q

what are the side effects of neuroleptic drugs

A

acute dystonia (dopamine receptor antagonism effect)
tardive dyskinesia (dopamine receptor antagonism effect)
anti-emetic effects
blockade action at histamine receptor
weight gain
sedation
hyperglycaemia

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3
Q

what are the features of neuroleptic drugs

A

treat positive symptoms but not negative symptoms
delayed effects - can take weeks
all neuroleptics block other receptors within the CNS in addition to dopaminergic receptors

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4
Q

what are neuroleptics

A

dopamine receptor antagonists

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