anti-psychotics Flashcards
1
Q
what are the main neurotransmitter defects in schizophrenia
A
too much dopamine
too little glutamate
2
Q
what are the side effects of neuroleptic drugs
A
acute dystonia (dopamine receptor antagonism effect)
tardive dyskinesia (dopamine receptor antagonism effect)
anti-emetic effects
blockade action at histamine receptor
weight gain
sedation
hyperglycaemia
3
Q
what are the features of neuroleptic drugs
A
treat positive symptoms but not negative symptoms
delayed effects - can take weeks
all neuroleptics block other receptors within the CNS in addition to dopaminergic receptors
4
Q
what are neuroleptics
A
dopamine receptor antagonists