NSAIDs Flashcards
1
Q
how do NSAIDs work
A
inhibit COX
this prevents the production of prostanoids from arachidonic acid
prostanoids are lipid inflammatory mediators: prostaglandins, prostacyclins, thromboxanes
2
Q
what is unique about paracetamol
A
no anti-inflammatory effect therefore not a true NSAID
3
Q
what are the side effects of NSAIDs
A
renal toxicity
CVS effects - hypertension, MI, stroke
stomach ulcers
