papillomaviruses, poxi, & asfarvius

Question 1

Answer 1

Question 2

Answer 2

Question 3

what are two different types of orthopoxviruse?

Answer 3

camelpox
monkeypox

Question 4

what are two examples of capripoxviruses?

Answer 4

sheep/goat pox
lumpy skin disease

Question 5

what is an example of leporipoxvirus?

Answer 5

rabbit myxoma virus

Question 6

what is the size of poxvirus?

Answer 6

largest virus >200nm

Question 7

how does poxvirus enter and infect to the host?

Answer 7

intermediate gene expression and DNA replication in the cytoplasm

Question 8

what are the clinical signs of poxvirus?

Answer 8

skin lesions (vesicles and scabbing)

Question 9

how does poxviruses evade the immune system?

Answer 9

stealth and mimicry

Question 10

when there is a cow with oronasal lesions what is an important differential to have?

Answer 10

FMD

Question 11

where is bovine papular stomatitis found?

Answer 11

worldwide distribution

Question 12

is bovine papular stomatitis zoonotic?

Answer 12

yes

Question 13

where is off/contaagious ecthyma found?

Answer 13

worldwide distribution

Question 14

is orf /contagious ecthyma zoonotic?

Answer 14

yes

Question 15

are bovine papular stomatitis and contagious ecthyma a foreign animal disease (FAD)?

Answer 15

no

Question 16

what species does myxomatosis target?

Answer 16

rabbits (European)

Question 17

is myxomatosis a foreign animal disease?

Answer 17

yes

Question 18

is lumpy skin disease a foreign animal disease?

Answer 18

yes

Question 19

what tissue does lumpy skin disease affect?

Answer 19

endothelial cell damage

Question 20

what tissue does sheep/goatpox virus infect?

Answer 20

dermal/pulmonary lesions

Question 21

is sheep/goatpox a foreign animal disease?

Answer 21

yes

Question 22

what does tissue does camel pox infect and what specific type of camel

Answer 22

old world camels
dermal/resp tract lesions

Question 23

is camelpox a FAD?

Answer 23

yes

Question 24

what is the mode of transmission for poxviruses?

Answer 24

vector (mechanical)
direct contact
zoonotic

Question 25

how do you prevent and control poxviruses?

Answer 25

vaccination control vectors isolation/slaughter

Question 26

which poxiviruses are FAD?

Answer 26

myxomatosis lumpy skin disease sheep/goat pox camelpox sealpox

Question 27

what poxivriuses are zoonotic?

Answer 27

cowpox orf camelpox sealpox

Question 28

what tissues does myxomatosis target?

Answer 28

skin and lymphocytes

Question 29

what tissue does sealpox infect?

Answer 29

skin and mucosa

Question 30

how and where do poxivriuses replicate both within a cell and within the host?

Answer 30

poxiviruses replicate in the cytoplasm, most commonly in dermal/musocal tissues

Question 31

how are poxivriuses infections manages and prevented?

Answer 31

vaccinations where available, control of vectors and isolation/slaughter od affected animals

Question 32

how and where does papillomaviruses replicate within host and cell?

Answer 32

endocytosis within basal squamous epithelial cells

Question 33

what are the clinical signs of papillmaviruses?

Answer 33

proliferative lesions (warts) of the epithelium

Question 34

what is the treatment for papillmaviruses?

Answer 34

excision cryosurgery radiation, chemo spontaneous regression (occasionally)

Question 35

which tissues do papillmomaviruses target and how does that play a role in transmission?

Answer 35

epithelial cells -transmission via contact, fomites +/- vectors

Question 36

how and where does papillomavirus replicate within a cell? within the host? how does that help them evade the immune system?

Answer 36

within the nucleus of the epithelial cells through a non-lytic process which helps avoid triggering immune system

Question 37

where is African swine fever contained before 2007?

Answer 37

Question 38

where has African swine fever spread to 2007-present?

Answer 38

Question 39

what makes African swine fever unique among DNA viruses?

Answer 39

only known DNA virus with biological arthropod vector

Question 40

what are the clinical signs of African swine fever?

Answer 40

1. paracute (sudden death) 2. acute (fever, hemorrhage, splenomegaly) 3. subacute (pneumonia)

Question 41

how is African swine fever transmitted?

Answer 41

tick-borne Contact with infected skin or pork products

Question 42

what is the treatment and prevention for African swine fever?

Answer 42

-depop/decontaminate/ repop -prevent exposure -DIVA incompatible, no vax

Question 43

what does the term "DIVA" mean WRT vaccine development?

Answer 43

ability to Distinguish Infected from Vaccinated Animals -requirement for efficiency separating true infections from animals which have been vaccinated in endemic areas