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herpes !! Flashcards

1
Q

herpes that infect horses

A

EHV 1
EHV 4

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2
Q

herpes that infect cattle

A

BHV 1
oHV2
AlHV11/2 (exotic MCF)

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3
Q

herpes that infect chickens

A

ILT
Marek’s disease

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4
Q

herpes that infect swine

A

pseudorabies
CMV

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5
Q

herpes that infect dogs

A

canine herpes virus
pseudorabies

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6
Q

herpes that infect cats

A

FHV

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7
Q

herpes that infect primates

A

herpes B virus

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8
Q

on histo how can you determine it is herpes?

A

intranuclear inculsion bodies

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9
Q

what are commonalities across all herpes infections?

A

majority of adults are latently infected (affects test interpretation)

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10
Q

can vaccination help with herpesvirus?

A

can help mitigate clinical signs, may not prevent infection

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11
Q

what is important to diagnose herpesviru?

A

clinical presentation and history

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12
Q

what does EHV cause?

A

abortions (mid-late pregnancy)
CNS effects

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13
Q

what does EHV 4 cause?

A

respiratory disease

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14
Q

how can EHV 1&4 cause transmission?

A

direct and indirect transmission through respiratory secretions, aborted fetus/placenta

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15
Q

what equine herpesvirus is associated with neurologic disease?

A

EHV1

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16
Q

how does EHV1 cause damage to the cell

A

CNS endothelial cell/vascualr damage

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17
Q

what is the treatment for equine herpesvirus?

A

supportive care
anti-inflammatories
-antivirals?

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18
Q

how to prevent equine herpes virus?

A

-isolation/restricting movement of affected animals or new introductions
-vaccinations

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19
Q

what is the vaccination protocol for equine herpes virus?

A

-foals: 4-6 months, booster
-high-risk animals: race, show animal
-pregnant mares: q2mons using inactivated vax

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20
Q

what disease complex is infectious bovine rhinotracheitis apart of?

A

bovine respiratory disease complex

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21
Q

what does infectious bovine rhinotracheitis cause?

A

abortions
conjunctivitis

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22
Q

what does bovine herpesvirus 1 cause in cattle?

A

abortions

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23
Q

what is the transmission and pathogenesis of IBR, bovine conjunctivitis?

A

direct contact
stressful events

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24
Q

what does ovine herpesvirus 2 cause?

A

endemic malignant catarrhal fever

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25
what symptoms does malignant catarrhal fever cause?
excessive discharge of mucud in URT -common asymptomatic infection
26
what species is OHV2/ endemic malignant catarrhal fever fatal in?
fatal bison, deer and antelope
27
alcelaphine herpesvirus1/2 also know as and what species common in?
exotic malignant catarrhal fever -common in African wildebeest
28
can you distinguish between endemic and exotic MCF?
clinically indistinguishable
29
how do you diagnose bovine herpesvirus?
serology fluorescent antibody test PCR
30
treatment for bovine herpes viruses?
vaccination isolation/separation
31
FHV1 is also apart of what disease?
feline viral rhinotracheitis
32
what does FHV1 cause in cats?
upper respiratory tract infection
33
how can you diagnose FHV1?
PCR FA
34
what can reactivate latent infections of feline herpesvirus?
steroids
35
what type of environment does canine herpesvirus 1 need?
temperature dependent replication
36
acute symptoms of infectious laryngotracheitis?
severe dyspnea, cough
37
subacute symptoms of infectious laryngotracheitis?
nasal/ocular discharge anorexia/lethargy decrease egg production
38
what can Marek's disease infected chickens survive in for months?
may survive for months in feather danger
39
what does Mareks disease target in the body?
virus targets T cells producing neoplastic cells
40
what does the neural form of Mareks disease affect ini the body?
peripheral nerves (sciatic) and CNS
41
what does the visceral form of Marek's disease affect in the body?
internal organs and feather follicles
42
what are the three forms of Marek's disease?
neural peripheral ocular form
43
how do you diagnose herpesvirus in chickens?
clinical signs and history pathology PCR
44
what is the treatment for herpesvirus in chickens?
culling affected animals
45
how can you prevent herpesvirus in chickens
biosecurity genetic resistance vaccination
46
what is the reservoir species for pseudorabies?
swine
47
where does pseudorabies reside during latency?
trigemina ganglion
48
symptoms of pseudorabies in the pig reservoir
age-associated survival and symptoms -younger pigs worse
49
who are the dead-end hosts for pseudorabies and what are their symptoms?
all other domestic species -2-3 day survival -pruritus, CNS signs
50
pathogenesis of pseudorabies in swine
1. oral exposure 2. viral replication in oropharyngeal epithelium 3. spread to regional lymph node via lymphatics 4. spread to CNS via PNS 5. latency established in trigeminal ganglion
51
what are the clinical signs of pseudorabies in swine?
neonatal pigs is 100 fatal weaned pigs: resp older pigs: low mortality
52
what is the treatment and control protocol for pseudorabies in domestic animals?
depopulation all-in, all-out vaccination
53
what does porcine cytomegalovirus (herpesvirus) cause in swine and at what age is it most apparent?
rhinitis and conjunctivitis most apparent neonatal pig
54
what is the herpes virus of ducks?
duck viral enteritis
55
what herpes viruses don't have a vaccine available?
MCF (ruminants) CMV (swine)
56
57
when are herpesviral vaccine given? what factors affect the timing of vaccination?
typically young animals and those most at risk are vaccinated- including pregnant animals that show animals in small animals herpesvirus vaccines are common components of regular vaccine schedules
58
what factor complicate herpesviral diagnosis?
latency can make distinguishing active infection from viral latency difficult while also sequestereing the virus to specific locations which are difficult to sample
59
how does adenovirus replicate?
drive cell into the S phase (DNA synthesis)
60
what are the clinical presentations for canine adenovirus 1 (ICH)?
blue eye disease -conjunctivits -type III hypersensitivity
61
how is canine adenovirus 1 transmitted?
CAV-1 MLV vaccines may cause blue eye
62
how is canine adenovirus prevented, how is CAV-2 used in routine vaccines?
DH(L)PPv vaccine incorporate CAV-2 which protects against CAV-1
63
is CAV 1 or CAV 2 more severe?
CAV 1
64
what is CAV 2 a potential component of?
component of canine tracheobronchitis
65
how can you diagnose canine adenovirus 1 and 2?
serology PCR
66
egg drop syndrome is also know as
duck adenovirus 1
67
what is egg drop syndrome/ duck adenovirus pathogenesis of thee eggs?
pale eggs-> soft eggs-> shell-less eggs no "drop" in production
68
what must you distinguish egg drop syndrome from?
Newcastle disease, AI
69
how do you control egg drop syndrome?
biosecurity cleaning litter
70
what care the more common adenovirus infections in veterinary species?
canine adenovirus 1&2 EDS '76 AHD of deer
71
how do adenoviruses replicate and how can we make use of adenoviruses in medicine?
-they induce the cell to divide by activating suppressor genes and are released by cytolysis -some can result in latent infections -adenoviruses can be modified to target very specific cell types and only those which are dividing=chemotherapeutics
72
what clinical signs are seen with canine adenovirus infections? what is the basis for the formation of blue eye in CAV 1 infections?
-URT +/- cardiovascualr disease - blue eye is result of type III hypersensitivity reaction
73
why is CAV2 used in routine vaccines if CAV-1 is more severe?
CAV-1 vaccinations can cause disease and CAV-2 has some cross-protection
74
how do infections with egg-drop syndrome '76 present? why is this a misnomer?
pale, soft eggs, sometimes progessing to shell-less eggs. no drop production is seen

microbio II (16 decks)

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