aspergillus Flashcards
what causes sinonasal disease in dogs (esp dolichocephalic) and sometimes in cats?
A. fumigatus
what causes air sacculitis in birds?
A. fumigatus
what causes guttural pouch mycosis in horses?
A. fumigatus
what can cause hepatotoxicity in an animal due to compost or moldy feed?
A. flavus
what is a clinical sign due to sinonasal disease in dogs and cats?
chronic mucopurulent nasal discharge
(caused by A. fumigatus)
what is the diagnosis for sinonasal disease?
*histopathology
imaging, rhinoscopy, culture, serology
in what specific species does A. fumigatus most likely effect?
air sacculitis in turkeys
what are the clinical signs of airsacculitis in birds?
respiratory +/- systemic diseases
what could be the causes of air sacculitis?
A. fumigatus
moldy bedding material and feed
what is the diagnosis of air sacculitis?
presence of lesions
what is the treatment for air sacculitis?
difficult due to lack of approved antifungals for avians
how do you prevent air sacculitis in birds?
clean bedding
replace feed
reduce stress and concurrent immunosuppresion
what does A. fumigatus cause in the guttural pouch mycosis in horses?
nasal discharge/epistaxis
what are the clinical signs of guttural pouch mycosis?
-chronic URI (discharge and epistaxis)
-CNS signs (Horners syndrome)
what is the diagnosis of guttural pouch myosis in horses?
history
clinical signs
endoscopy
what is the treatment for guttural pouch mycosis?
angiographic guided embolization
how is aspergillus transmitted (overall)?
environmental exposure
how is aspergillum diagnosed (overall)?
imaging, histopath, culture, serology
how is aspergillum treated (overall/generally )
-topical azoles +/- surgical debridement (sinonasal)
-catheterization and embolization (guttural pouch)
how do you calculate morbidity rates?
the number of the sick and dead over/divided by the entire population
how do you calculate the mortality rate?
the dead over/divided by the total population
how do calculate the case fatality rate?
you take the number of deaths and divide by the number of morbidity (dead and sick)
how is odds ratio calculated?
describe SIR model and how can it be used to help understand and manage disease trasmission?
