Papillomaviridae

Question 1

What gene does malignant papllimoma virus relication disrupt and which are still intact?

Answer 1

Disrupts E2- viral repressor

E6 and E7 are intact

Question 2

Bovine Papillomatosis
Host
Transmission

Answer 2

Cattle
Can infect horses
fomites, venereal

Question 3

What is Bovine Paillomatosis Fibropapilloma caused by?

Answer 3

bovine papillomavirus types 1,2 and 5

Question 4

Where do young bulls often get Fibropapillomas?

Answer 4

Penis, renders them no value as bull studs

Question 5

Cutaneous papillomas in bovines is caused by

Answer 5

Bovine papillomavirus type 3

Question 6

Ingestion of what plant can cause invasive carcinoma of the alimentary tract in bovines? What virus causes this?
What virus causes enzootic hematuria after eating the same plant?

Answer 6

Braken Fern Bovine
papilloma virus 4- alimentary tract carcinoma
Paillomavirus 1 and 2- urinary bladder cancer

Question 7

Bovine Papillomatosis
Dx
Treatment
Prev

Answer 7

TEM, PCR
Sx excision, cryosx w/ liquid nitrogen
Podophyllin DMSO
Bovine interferon-a 
Prev: Vx

Question 8

How is canine oral papillomatosis characterized histologically?

Answer 8

Epithelial hyperplasia and cytoplasmic vacuolization (koilocytosis)

Question 9

What is the most common neoplasm in horses and what is it caused by? Can it metastisize?

Answer 9

Equine Sarcoid
Bovine papillomavirus 1 or 2
Can’t metastisize

Question 10

Susceptable Breeds for Equine Sarcoids

Answer 10

Arabian
Appoloosa
American Quarter

Question 11

Less susceptible breeds for Equine Sarcoids

Answer 11

Standardbred

Throughbred

Question 12

Where do equine sarcoids normally occur?

Answer 12

Traumatized areas

Question 13

What is the difference between benign and malignant papillomas?

Answer 13

Benign are episomal, malignant is viral DNA integrated into host DNA