Pancreatic tumours

Question 1

List the benign cysts of the pancreas

Answer 1

Premalignant
* Intraductal Papillary Mucinous Neoplasia(IPMN)
* Mucinous Cystic Neoplasia(MCN)
* Solid Pseudopapillary Neoplasia(SPEN)

True Benign/ Noncancerous
* Pseudocysts
* SerousCysticNeoplasia(SCN)
* (Choledochal cysts, amoebic cysts, lymphoreticular cysts, and post-traumatic cysts)

Question 2

List the malignant cysts of the pancreas

Answer 2

– NET: neuroendocrine tumours
– PDAC:
– Mucinous cystadenocarcinomas

Question 3

What is imaging used for in pancreatic tumours

Answer 3

Need to determine:
* Communication with main PD
* Size and number of cysts
* Mural nodules
* Other characteristic features

Question 4

Explain Mucinous Cystic Neoplasia

Answer 4

• Characterized by estrogen and progesterone receptor positive ovarian-like sub-epithelial stroma
• Classified in benign mucinous cystadenomas, borderline mucinous cystic neoplasms (MCNs), and mucinous cystadenocarcinomas (MCACs).

Question 5

Explain pseudopapillary neoplasia

Answer 5

• Occur mostly, but not exclusively, in young women
• The morphology is highly variable with cystic and solid parts.
• Low malignant potential

Question 6

Explain Serous cystic neoplasia

Answer 6

• SCN’s 15 to 20 % of cystic neoplasms of the pancreas.
• Approximately 75 % occur in females.
• SCNs of the pancreas are thought to be benign