Chronic pancreatitis Flashcards
What is the definition of chronic pancreatitis
- Benign inflammatory and fibrosing disorder
- Progressive and irreversible morphological change
- Permanent loss of exocrine and endocrine dysfunction
What are the aetiology of chronic pancreatitis
Alcohol
Autoimmune
Miscellaneous
Idiopathic
How is chronic pancreatitis diagnosed
Histology is gold standard but impractical
Based on clinical and morphological features of CP
What are the clinical manifestations of CP
Abdo pain
Pancreatic exocrine/endocrine insufficiency
Complications
Which imaging modalities are used in chronic pancreatitis
Abdo x-ray - indicated due to being able to see calcifications
US - difficult due to being retroperitoneal organ
Abdo CT
Endoscopic US
MRI, endoscopic retrograde pancreatography
What is the approach to a patient with chronic pancreatitis
Determine aetiology
Look for consequences
Look for complications
Initiate multimodal management
What are the investigations for CP
FBC, U&E, LFT
HbA1c
Clacium-magnesium-phosphate
Vit D level
Faecal elastase
Pancreas protocol CT scan
What does the multimodal treatment of chronic pancreatitis
Gastro-entorologist (HPB surgeon)
Endocrinologist
Dietician
Psychologist/psychiatrist
Social worker
Pain specialist
