Pancreatic and Biliary Pathology Flashcards
Acute pancreatitis
Reversible parenchymal injury with inflammation
Biliary tract dz and alcoholism are 2 most comon
Pathology of acute pancreatits
Edema Necrosis Acute inflammation - neutrophils Fat necrosis Hemorrhage due to BV dsamage
Acute pancreatitis dx
Typical pain
CT scan
Amylase/lipase…lipase remains elevated longer nad is more specific
Hypocalcemia
Precipitation of calcium in fat necrosis of pancreatitis
Poor prognostic sign
Chronic panc dx
Calcification by US and Ct
Diabetes
Malabsorption with steatorrhea
Panc cancer causes
SMoking is leading preventable
Peutz-Jeghers syndrome with BRCA2
Panc cancer dx
Progressive jaundice (head)
Trosseau sign…platelet activating factors and pro-coagulants
Can get CA19-9 for FOLLOWUP
Serous cystadenoma
Microcystic adenoma
Benign
Older females
Sponge-like
GLycogen
Mucinous cystic neoplasm
Ovarian type stroma and most are in tail
IPMN
More in mlaes and at head
Solid psuedo-papillary tumor
Solid-cystic tumor
Young women
B-catenin mutation
Insulinoma
Whipple triad - hypoglycemic attacks…blood sugar under 50 mg….sx relieved by glucose
Gastrinoma
Due to excess gastrin secretion and get recurrent PUD
AI panc
Painless obstructive jaundice
Clinically and radiologically suspicious for panc cancer
IgG4
Can tx with steroids
Risk factors for cholesterol stones
Old age
Female sex hormones, pregnancy, oral contraceptives
Obesity
