Esophagus and Stomach Flashcards
Structure
UES at C5-6 with cricopharyngeus muscle…runs to T10
No serosa
Esophageal duplication cysts
May cause dysphagia but often found incidentally
Shatkis rng
Thin membranous ring at the squamo-columnar jxn
Tx with dilation
Reflux esopahgitis extra esoph
Cough, wheeze, sore throat and ear pain
GERD on histo
Basal cell layer thickneing with infiltrate of neutrophils
Who should get endoscopy
Failure to respond to PPI after 4-8 weeks Weight loss Dysphagia Men>50 FH of esophageal cancer
Eosino esoph on endscopy and ass sx
Furrows and potentially grooves
Atopy, failure to respond to PPI
Can give topical steroids
Herpes esophagitis
Multinucleated cells with ground glass appearance
CMV esophagitis
Large cells with promintnent intranucelar inclusions
Barrett esophagus
Metaplastic olumnar epithelium replaces suqamous epithelium in distal esophagus
Comp of GERD
Inc risk of adenocarcinoma
Surv every 3-5 if no dysplasia nd annually if low grade
Tx of HGD
Ablation
Esophagectomy
Surveillance
SCC
Drinking and smoking
Black males more
High risk areas and Vit E def
Vit D inverse associatino
Etiology of SCC
Genetic predispotiion with HPV infection risk
SCC location
MIddle 1/3 is most common
Lacerations
Most commonly in alcoholics
Mallory weiss tear syndrome
Boerhaave syndrome - trnamsural
Achalasia
Will present with dec of absent peristalsis
Could be from Chagas dz or destruction of myenteric plexus
Look for bird beak
H. pylori
Urease (+), gram neg
Fastidious
Only grastric type mucosa
Flagella
Urease
H pylori associations
Chronic and acute gastirtis
PUD
Gastric carcinoma
MALT
Urea breaht test
test of choice for confirming eradication
Acute gastric erosion
NSAIDs and aspiriin
Severe stress
From mucosal hypoperfusion, impairment of local defesne or hypersecretion of gastric acid
Shallow and sx with coagulative necrosis
AI Gastritis
Type A chronic
Of the BODY
Abs to pareital cells and intrinsic factors so may get pernicious anemia
Carcinoid tumor and gastric cancer
Hypochlorhydria with hypergastrinemia
Multifocal atrophic gastritic
Type B
ANTRUM
H.pylori
Normal
Class of gastric cancers
Intestinal - polypoid and fungating due to the diet
Diffuse - ulcerative and poorly diff with SIGNET ring cells