pancreas Flashcards
PANCREATITIS OCCURS WHEN?
the pancreas becomes damaged and malfunctions as a result of increased secretion and blockage of ducts
What is an acute attack of pancreatitis commonly related to?
alcoholism & biliary tract disease
Patients with pancreatitis typically present with
moderate to severe tenderness in the epigastrium radiating to teh back
when swelling does occur, the gland is hypoechoic to anechoic and is less echogenic than the liver becuase of the increased prominence of?
lobulations and congested vessels
the pancreatic duct may be obstructed in acute pancreatitis as a result of?
inflammation, spasm, edema, swelling of the papilla, and pseudocyst
fluid collections around the pancreatic ____, along the ____ spaces, within the ____ pouch, and around the ____ may be present in a patient with acute pancreatitis
*bed *pararenal *Morison’s *duodenum
patients with acute pancreatitis may develop complications, such as?
pseudocyst, phlegmon, abscess, hemorrhage, and duodenal obstruction
courvoisier’s gallbladder
enlargement of the GB caused by a slow, progressive obstruction of the distal CBD from an external mass, such as adenocarcinoma of the pancreatic head
cystic fibrosis
hereditary disease that causes excessive production of thick mucus by the endocrine glands
hypercalcemia
elevated levels of calcium in the blood
hyperlipidemia
congenital condition in which elevated fat levels cause pancreatitis
ileus
dilated loops of bowel without peristalsis; associated with various abdominal problems, including pancreatitis, sickle cell crisis, and bowel obstruction
leukocytosis
abnormal increase in WBC’s caused by infections
serum amylase
pancreatic enzyme that is elevated during pancreatitis
lipase
pancreatic enzyme that breaks down fats; enzyme is elevated in pancreatitis and remains increased longer than amylase
islets of Langerhans
portion of the pancreas that has an endocrine function and produces insulin, glucagon, and somatostin
insulin
hormone that causes glycogen formation from glucose in the liver and that allows circulating glucose to enter tissue cells
glucagons
stimulates the liver to convert the glycogen to glucose; produced by alpha cells
exocrine
the kind of pancreatic function that involves the production and digestion of pancreatic juice
endocrine
the kind of pancreatic function that involves the production of the hormone insulin
amylase
enzyme secreted by the pancreas to aid in the digestion of carbs
acini cells
cells that perform exocrine function
uncinate process
small, curved tip of the pancreatic head that lies posterior to the SMV
tail of the pancreas
tapered end of the pancreas that lies in the left hypochondrium near the hilus of the spleen and upper pole of the LT Kidney
superior mesenteric vein
lies posterior to the neck or body of the pancreas and anterior to the uncinate process of the gland
superior mesenteric artery
serves as the posterior border to the body of the pancreas
portal-splenic confluence
junction of the splenic and MPV; posterior border of the body of the pancreas
pancreaticoduodenal arteries
help supply blood to the pancreas along with the splenic artery
neck of the pancreas
small area of the pancreas between the head and the body; anterior to the SMV
head of the pancreas
lies in the C-loop of the duodenum; the gastroduodenal artery is the anterolateral border, and the CBD is the posterolateral border
duct of wirsung
largest duct of the pancreas that drains the tail, body, and head of the gland; it joins the CBD to enter teh duodenum through the amupulla of vater
duct of santorini
small accessory duct of the pancreas found in the head of the gland
dorsal pancreatic artery
branch of the splenic artery that supplies the body of the pancreas
common hepatic artery
forms the right superior border of the body and head of the pancreas and gives rise to the GDA
C-loop of the duodenum
forms the lateral border of the head of the pancreas
caudal pancreatic artery
branch of the splenic artery that supplies the tail of the pancreas
body of the pancreas
lies in the midepigastrium anterior to the SMA and SMV, AO, and IVC
lymphoma
malignant neoplasm that arises from the lymphoid tissues
obstructive jaundice
excessive bilirubin in the bloodstream caused by obstruction of bile from the liver.
pancreatic ascites
fluid accumulation by a rupture of a pancreatic pseudocyst into the abdomen (very dangerous)
pancreatic pseudocyst
-“sterile abscess” - enzymes accumulate in available space in the abdomen
pancreatitis
-inflammation of the pancreas -may be acute or chronic
pseudocyst
contains fluid but has no true endothelial lining membrane
The pancreas is located in the ________
retroperitoneal cavity
the pancreas is located posterior to the
-stomach -duodenum -proximal jejunum of the small bowel
pancreatic glad appears sonographically ________to slightly more ________ than the ____________.
-isoechoic -hyperechoic -hepatic parenchyma
posterior vascular landmarks of the pancreas are
-aorta -IVC
The head of the pancreas lies _____ to the ______
-anterior -IVC
SMV crossed ______ to the ______ of the head of the gland
-anterior -uncinate process
SMV crosses posterior to the _______ and ______ of the pancreas
-neck -body
the tortuous _________ is the ______ border of the pancreas.
-splenic artery -superior
the tail of the pancreas lies ______ to the _______
- anterior - left kidney
the tail of the pancreas is ______ to the left ________ and __________.
-posterior -colic flexure -transverse colon
the _______ enters the medial second part of the duodenum with the CBD at the ampulla of vater
- duct of wirsung
the ______ receives tributaries from lobules at right angle
duct of wirsung
blood supply for the pancreas is from the _______ and the __________
- splenic artery - pancreaticoduodenal arteries
the ______ is seen along the _______ border of the pancreas as it travels along the _______ aspect of the pancreas head
- gastroduodenal artery (GDA) - anterolateral - anterior
the CBD crosses the _____ aspect of the PV to the ____ of the proper hepatic artery
-anterior -right
the PV is ______ to the IVC
anterior
the pancreas is a _______ ( exocrine) and a _______ (endocrine) gland.
- digestive - hormaonal
diabetes mellitus
failure of the pancreas to furnish insulin
exocrine function is perform by _______ of the pancreas
acini cells
Sphincter of Oddi
-muscle surrounding the ampulla of vater - relaxes to allow pancreatic juices & bile to empty into the duodenum
the endocrine function is located in the _______ in the pancreas
islets of langerhans
beta cells are most prevalent and produce _______, a hormone that causes _______ formation from _______ to the liver
- insulin - glycogen - glucose
alpha cells produce _______, a hormone that causes the cells to release ________ to meet energy needs
-glucagons -glucose
_____ are the smallest composition of the endocrine tissue and produce __________
- delta cells - somatostatin
enzymes of the pancreas that become altered in pancreatic disease are
-amylase -lipase
the elevation in ________ concentration persists for a longer period in pancreatitis
lipase
_______ controls the blood sugar level in the body
glusose
what is the water technique used to image the pancreas with ultrasound.
- pt. drinks 32-300ml through a straw - in an erect or lateral decubitus - fluid dills the duodenal cap - outlines the lateral margin of the head of the pancreas - upright position allows air to move from the gastric antrum to the fundus of the stomach - causes the upper viscera to move downward for a better sonograhic window
when the pancreas is enlarged, the ______ border of the _____ may depict’a slight indentation
- anterior - IVC
Grey Turner’s sign
NECROSIS of the blood vessels results in the development of HEMORRHAGIC areas
phlegmon
- spread along facial pathways - causes diffuse inflammatory edema of soft tissue
chronic pancreatitis
- obstructed pancreatic duct -with a buildup of protein plugs -results in calcifications along the duct
how does a pseudocyst develops
pancreatic enzymes that escape the ductal system cause enzymatic digestion of surrounding tissue & pseudocyst development. The walls of the pseudocyst from various potential spaces in which escaped pancreatic enzymes are found. pseudocyst usually presents few symptoms until it becomes large enough to cause pressure on surrounding organ
the most common pseudocyst is in the
lesser sac
the lesser sac is ______ to the pancreas and ______ to the stomach
- anterior - posterior
A pseudocyst develops when ________ escape from the gland break down tissue to form _______ somewhere in the _______.
- pancreatic enzymes - sterile abscess - stomach
adenocarcinoma
the most common primary neoplasm of the pancreas
what are the clinical findings in a patient with carcinoma of the pancreas
- wt loss - painless jaundice - nausea - vomiting - changes in stool
lymphoma
the most frequent parapancreatic neoplasm