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pain syndromes Flashcards

1
Q

Affects more Americans than diabetes, heart disease and cancer combined

A

pain

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2
Q

the most common cause of long-term disability

A

chronic pain

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3
Q

Most common reason Americans access the health care system

A

pain

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4
Q

this kinda of pain alerts person to possible injury/condition

A

acute pain

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5
Q

this kind of pain is persistant, signals keep firing for weeks or years
There may be an initial trigger (injury or condition, serious infection, arthritis, cancer, etc.), but
many suffer w/o history of injury or condition

A

chronic pain

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6
Q

this kind of pain adversely affecting a person’s life physically, emotionally, and mentally
Can alter body at the cellular level

A

chronic pain

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7
Q

chronic pain includes

A

headaches, LBP, cancer, arthritis, neurogenic, and psychogenic (not due to past disease or injury)

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8
Q

pain classification

A

Can be based on pain physiology, intensity, temporal characteristics, type of tissue affected, or syndrome

Pain physiology (nociceptive, neuropathic, inflammatory)

Intensity (mild-moderate-severe; 0-10 numeric pain rating scale)
Time course (acute, chronic)
Type of tissue involved (skin, muscles, viscera, joints, tendons, bones)
Syndromes (cancer, fibromyalgia, migraine, others)

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9
Q

Caused by damage, injury, or inflammation to body tissue
Usually described as a sharp, aching, or throbbing pain
Usually associated with acute conditions

A

nociceptive pain

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10
Q

Associated with chronic pain
Occurs when there is damage, change, or problems to the peripheral nerves or CNS
Usually described as prickling, tingling or burning
Generally responds poorly to pain tx

A

neuropathic pain

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11
Q

A patient reports a pricking, tingling and burning sensation on the dorsum of her left hand. What type of pain is this patient describing?

a. Acute pain
b. Nociceptive pain
c. Chronic pain
d. Neuropathic pain
A

neuropathic pain

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12
Q

what is gate control theory?

A

Pain impulses are “influenced” by a gating mechanism in the dorsal horn

Stimulating touch or movement sensation can close the gate, limiting pain impulse transmission

“non-painful sensations override painful sensations”

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13
Q

gating mechaniskm is controlled by

A

Gating mechanism is controlled by the activity in the large and small fibers
Large-fiber (A–alpha or proprioception/movement, A-beta or touch) activity inhibits (or closes) the gate
Whereas small fiber activity (pain) opens the gate
When gate is closed, small diameter pain fibers do not excite the dorsal horn transmission neuron
If pain information reaches a threshold that exceeds inhibition

It “opens the gate” and pathways to experience pain
Gating mechanism is influenced by nerve impulses that descend from the brain

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14
Q

3 influences on opening and closing the gate:

A

Amount of activity in the pain fibers
Amount of activity in other peripheral fibers
Messages that descend from the brain

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15
Q

neurophysiology of pain modulation: circles consist of what in the brain?

A

Circuit consists of periaqueductal gray (PAG) matter in the upper brain stem, locus coeruleus (LC), the nucleus raphe magnus (NRM) and nucleus reticularis gigantocellularis (Rgc)

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16
Q

neurophysiology of pain modulation: contribute to what pathway?

this inhibits what?

A

the descending pain suppression pathway,

inhibiting incoming pain

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17
Q

neurophysiology of pain modulation: opiods interact with what?

this causes what?

A

Opioids interact with the opiate receptors at different CNS levels, causing secondary changes which lead to neuronal electrophysiological change and modulation of ascending pain information

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18
Q

neuropathic pain causes

A

Infections & viral conditions
Compressive
Autoimmune
Congenital/hereditary

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19
Q

chronic pain treatment

A

Medications, acupuncture, local electrical stimulation, and brain stimulation, as well as surgery, etc.
Some physicians use placebos
Psychotherapy, relaxation and medication therapies, biofeedback, and behavior modification
Chronic pain sufferers found to often have lower than normal levels of endorphins in spinal fluid

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20
Q

acupuncture activates what systems?

A

Acupuncture & electro-acupuncture may activate endorphin systems

21
Q

acupuncture is believed to stimulate what fibers? what do these fibers inhibit and enhance?

A

Believed to stimulate A-delta fibers mediating inhibition of pain impulses, and enhance descending pathway inhibition from midbrain

22
Q

post-acupuncture treatment has shown increased levels of what in CSF?

A

Post-acupuncture Tx shown to increase levels of endorphins in cerebrospinal fluid

23
Q

What is CRPS?

A

Complex Regional Pain Syndrome (CRPS) type I and II is a multifactorial disorder that is associated with an aberrant host response to tissue injury

30% of CRPS sufferers experience persistent pain and impairment for 2-6years following onset

CRPS can be resistant to therapies making management challenging for clinicians

24
Q

mechanism of CRPS

A

1) original injury initates a pain impulse carried by sensory nerves to CNS
2) pain impulses trigger impluses in sympathetic system which returns to the original site of injury
3) sympathetic impluse triggers inflammatory response causing the vessels to spasm leading to swelling and increased pain
4) pain triggers another response, establishing a cycle of pain and swelling

25
Formerly known as Reflex Sympathetic Dystrophy (RSD) Pain characterized as constant, extremely intense, and out of proportion to the original injury
CRPS
26
Typically accompanied by swelling, skin changes, extreme sensitivity, and can often be debilitating Usually affects one or more of the four limbs but can occur in any part of the body In over 70% of the victims it spreads to additional areas
CRPS
27
Progressive disease of the ANS, and more specifically, the Sympathetic Nervous System
CRPS
28
75% of those affected are women | Pain is primary component:
CRPS
29
Described as the most pain ever experienced “Imagine your hand was doused in gasoline, lit on fire, and then kept that way 24/7, and you knew it was never going to be put out”
CRPS
30
2nd component is Allodynia - extreme sensitivity to touch, loud or deep sounds, and/or vibration, where normal touch become pain
CRPS
31
CRPS SIGNS AND SYMPTOMS
Constant chronic burning pain, usually significantly greater than original event/injury Inflammation
32
prevention of CRPS
Multiple cast changes Neglect of limb/ anger with limb Reports “claustrophobia in cast” Reports “limb does not feel like my own” Allodynia Uncontrolled pain while in cast by two weeks Restricted unaffected joint motion while in cast
33
prognosis of CRPS
Varies from person to person Most children and teenagers have a good recovery Evidence suggests prevention is key Early treatment, particularly rehabilitation, helpful in limiting the disorder, but not yet been proven in clinical studies More research needed to understand the causes of CRPS, how it progresses, and the role of early treatment
34
OT Intervention in Pt’s with CRPS
Compensatory Approaches Use clinical-decision making skills to determine if compensatory approach is better fit for patient. Symptoms may be worsened by stress loading patients with CRPS Packman & Holly (2018) suggest unloading: Providing supportive wrist orthosis permitting functional use while minimizing pain Increasing physical demands when monitoring responses of clinical signs and patient symptoms
35
OT Intervention in Pt’s with CRPS
Remedial Approaches Management of allodynia, edema, ROM, and strength along with engagement in activities of daily living (ADLs) Exercise program to keep the painful limb moving to Improve blood flow and reduce circulatory symptoms, Improve the affected limb’s flexibility, strength, & function Prevent or reverse the secondary brain changes associated with chronic pain Management of psychological symptoms
36
Addressing Sensory Stimulation/Neuroplasticity in Pt’s with CRPS
Sequential activation of the cortical networks involved in sensory and motor processing corrects sensorimotor incongruence in afferent signaling from the affected limb. N = 51 single blind RCT with persons with CRPS1 and phantom limb pain. Slowly and smoothly adopt the movement portrayed in a card in each hand while looking in the mirror and repeated 2 times Decrease in pain
37
Addressing Sensory Stimulation/Neuroplasticity in Pt’s with CRPS
3-D augmented virtual reality using mirror visual feedback principles can correct sensorimotor incongruence to reduce neuropathic pain. N = 22; Patients see a projected image of themselves. When they move the unaffected limb, they see their affected limb moving. Patients had to reach for specific targets and the difficulty level of the task increased. 5 sessions (20 min each) over 1 wk Significant effect on pain reduction (while pain relief was not maintained in total between sessions, it never returned to baseline of previous session)
38
Addressing Psychological Distress Along with CRPS
Psychotherapy CRPS is often associated with profound psychological symptoms for affected individuals and their families May develop depression, anxiety, or post-traumatic stress disorder, all of which heighten the perception of pain and make rehab efforts more difficult Acceptance-based coping is reflected by increased activity N = 30, Observational cohort (i.e. no intervention); “proof of principle study” Those with good coping mechanisms has lower pain and increased participation in activity; suggesting acceptance-based coping may be beneficial to those with CRPS.
39
CRPS medications
Medications Sympathetic Nerve Block Surgical Sympathectomy
40
CRPS medical treatment
Neurostimulation Along the pain pathway, include near injured nerves (peripheral nerve stimulators) Outside the membranes of the brain (motor cortex stimulation with dural electrodes) Within the parts of the brain that control pain (deep brain stimulation) Recent option involves the use of repetitive Transcranial Magnetic Stimulation (rTMS) Magnetic currents applied externally to the brain
41
placebo effect for CRPS
Placebo – substance or inactive treatment made to appear as active treatment Often used in clinical trials (research) to compare differences in effect between the active treatment and inactive treatment The “effect” seems to affect how a person feels, and may change symptoms as a result Usually refers to relieving symptoms Nocebo effect refers to worsening of symptoms after a placebo
42
Common and complex chronic pain disorder that affects people physically, mentally and socially Can be extremely debilitating and interfere with basic daily activities
fibromyalgia
43
A syndrome rather than a disease | Also called fibromyositis and fibrositis
fibromyalgia
44
Characterized by chronic widespread pain, multiple tender points, abnormal pain processing, sleep disturbances, fatigue and often psychological distress
fibromyalgia
45
symptoms of fibromyalgia
Pain Is profound, chronic and widespread can migrate to all parts of the body and vary in intensity Has been described as stabbing and shooting pain and deep muscular aching, throbbing, and twitching Fatigue All-encompassing exhaustion that can interfere with occupational, personal, social or educational activities Profound exhaustion and poor stamina
46
fibromyagia diagnosis
Doctors must rely on patient histories, self-reported symptoms, physical examination No laboratory tests available for diagnosing fibromyalgia Takes an average of five years for an FM patient to get an accurate diagnosis
47
what must a FM patient do to receive a diagnosis of FM?
the patient must meet the following diagnostic criteria: Pain in all four quadrants of the body for at least 3 months Tenderness or pain in at least 11 of the 18 specified tender points when pressure is applied
48
fibromyalgia trigger points
cervical vertrabae, 2nd rib, lateral epicondyle, knee back of head, supraspinatus, traps, hip, and butt
49
a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues.
fibromyalgia

human conditions (28 decks)

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