Pain Part 1 Flashcards

1
Q

external environment information is

A

sensory

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2
Q

internal environment information is ____ afferent

A

visceral

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3
Q

4 elementary attributes of stimulus coding

A

modality
location
intensity
duration

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4
Q

sensory information which we are aware

A

sensation

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5
Q

understanding of the stimulus

A

perception

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6
Q

modalities of stimuli

A

mechanical
light
chemical
temperature

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7
Q

law of specific nerve energies

A

a given sensory receptor is specific for each modality

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8
Q

chemoreceptors include

A

taste
smell
pain

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9
Q

chemoreceptors detech pain by

A

chemicals dissolved in ECF

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10
Q

what detects acceleration

A

hair cells- mechanoreceptors

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11
Q

sensations from skin, muscles, tendons, joints

A

somatic sensation

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12
Q

temperature uses ___ proteins

A

transient receptor potential (TRP)

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13
Q

direct afferent receptor configuration

A

stimulus acts directly on sensory receptor, opens ion channel, triggers AP

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14
Q

indirect afferent receptor config

A

stimulus acts on specialized cell, which opens ion channel and triggers an AP
- involves Ca2+ influx

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15
Q

sensory unit

A

one afferent neuron and all of its sensory receptors

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16
Q

receptive field

A

area of the receptive surface of an afferent

17
Q

which receptors are steady pressure

A

merkel cells

ruffini endings

18
Q

which receptors are tingling/ vibrations

A

meissner corpuscle

pacinian corpuscle

19
Q

which receptors are rapidly adapting

A

meissner

pacinian

20
Q

which receptors are slowly adapting

A

merkel and ruffini

21
Q

change environmental stimuli into electrical signals

A

transduction

22
Q

frequency of AP and population of activated receptors codes

A

stimulus intensity

23
Q

somatosensory pathway

A

first order - synapse in spinal cord - second order - thalamus synapse - third order - cortex

24
Q

modality is coded through

A

specialized pathways that project to specific cortices

25
Q

location is coded through

A

specific regions of the brain + size of receptive field

26
Q

where is the best 2 point discrimination found

A

lips

27
Q

where is the worse 2 point discrimination found

A

calf

28
Q

TRPs are _____ channels

A

nonselective cation

29
Q

TRPV1

A

activated by heat, acids, capsaicin

30
Q

TRPA1

A

mechanical, cold, chemical

31
Q

TRPM8

A

responds to menthol- cool receptor

32
Q

acid sensing ion channels are sensitive to _____ and are found on

A

pH changes

nociceptors