pain, fever, & inflammation Flashcards
1
Q
- doesn’t treat inflammation
- reduces fever & decreases minor pain
- 4grams max over 24h
- duration 3-4h
- AE: hepatotoxicity, renal failure
- CI alcohol & hepatic impairment
A
acetaminophen
2
Q
what is treatment for OC acetaminophen?
A
acetylcysteine
3
Q
- relieves pain, reduces fever
- diminish inflammation by blocking prostaglandins
- suppress platelet aggregation
- risk for bleeding
A
aspirin
4
Q
if aspirin is given to children, what can occur?
A
reye’s syndrome
5
Q
- relieve mild to moderate pain such as dysmenorrhea
- treat inflammation related to RA and OA
- can take w/ food/liquid to decrease gastric irritation
- older adults w/ high use are at risk for bleeding
- can worsen/cause kidney impairment
A
ibuprofen
6
Q
- mild to moderate pain (dysmenorrhea)
- longer acting (12h)
- more likely to have GI side effects
A
naproxen sodium (Aleve)
7
Q
- relieves pain associated w/ RA< OA, ankylosing spondylitis, bursitis, tendonitis, & gouty arthritis
- use only in acute gout attacks
- BEERs list
- assess for CNS, GI, cardiac bleeding effects
A
ketorolac
8
Q
cardinal s/s inflammation include
A
pain, fever, redness, swelling, malaise, drainage of exudate
9
Q
fever
A
100.4
10
Q
- produces joint pain inflammation & degernation
- Tx aspirin, acetaminophen, NSAIDs
A
osteoarthritis
11
Q
- overproduction uric acid
- causes tophi, enlarged joint, pain/swelling
- Tx NSAID, corticosteroid
A
gout
12
Q
- short-term Tx inflammatory disorders
- doesn’t cure disease
- AE: HTN, hyperglycemia, immunosuppression, impaired healing, mood changes, wt gain , sodium/fluid retention
- CI live vaccine use
- must be tapered off
A
prednisone & methylprednisolone sodium succinate
13
Q
what time should steroids be given?
A
0900 to mimic peak diurnal concentration
14
Q
T/F: grapefruit juice can be given with antigout medication
A
F
15
Q
- adrenal insufficiency
- not enough cortisol —> hypotension
A
addison’s disease
16
Q
- exhausted body stores of glucocorticoids in a pt w/ adrenal insufficiency after trauma, surgery, or other –> can lead to shock
A
addisonian crisis
17
Q
- key hormone in RAAS system & stress response
- increases BP, HR
- stimulates retention fluid & sodium
- deficiency causes increases renal sodium loss & enhances potassium reabsorption –> BP drop due to loss of sodium
A
alosterone
18
Q
- excess cortisol production & circulation in bodu
- can lead to adrenal crisus
A
cushing’s disease
19
Q
- lipid soluble hormones
A
glucocorticoid
20
Q
- affect every aspect of inflammatory & immune responses
- important in hemostasis & metabolic processes
- suppress severe inflammation
- secretion controlled by hypothalamus
A
corticosteroid