dyslipidemia Flashcards
1
Q
- most powerful class for LDL reduction
- avoid large amounts grapefruit juice/fruit
- AE: n/v, abdominal pain, rach, headache, myopathy, rhabdomyolysis
- report coca-cola colored urine
- monitor liver function & lipid levels
A
atorvastatin (Lipitor)
2
Q
- decrease LDL, used in combination w/ other drugs
- powder mixed w/ fluids, take with food
- AE: bloating, diarrhea, n/v, constipation
- admin other drugs 1h before or 4h after
A
cholestyramine (Questran)
3
Q
cholestyramine is a
A
bile acid sequestrant
4
Q
- decreases triglycerides & increases HDL
- metabolized by liver, excreted by kidneys
- admin w/ food (increases absorption)
- if given w/ statins can increase rhabdomyopathy
A
fenofibrate
5
Q
- only recommended for use in pt w/ triglyceride levels >500 who haven’t been able to acheieve desired response/don’t tolerate other drug therapy
- vitamin B3
- AE: skin flushing, pruritus, gastric irritation, increases BG
A
nicotinic acid/niacin
