Pain Clinical Correlates Flashcards

1
Q

Pain

A

Unpleasant sensory and emotional experience associated with actual or potentia l tissue damage

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2
Q

Acute pain

A

Hurt=harm…avoidance decreases damage

Clear path

Fixed end point, immobilization, meds

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3
Q

Chronic pain

A

Hurt does not = harm and fear avoidance cycel

Multifactorial

No end point, immobilization owrse, meds beware

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4
Q

Tx of actue and chronic

A

Acute - aggressive, coping skills secondary, intensive hospital, physio evolving

Chronic - step wise, coping skills important, outpatient only, physio established

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5
Q

Mech/noci pain

A

Sharp, dull, ache

Tissue destruction, inflammationan, somatic pain, visceral pain

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6
Q

Neuropathyuic pain

A

Bruning, stinging, pins and needles

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7
Q

Allodynia, dysethenia, hyperalgesia

A

Non painful sensation now painful
Abnormal sensation
Increases ensitivity to pain

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8
Q

Fibers types

A

Mecahno - Abeta - fast

Pain - adelta-fast
C - slow

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9
Q

Pain pathway

A

Can be excitatory or inhibitory

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10
Q

Anexiety and depression

A

Lateral pathway - helps ID location, type intensity

Medial - helps drive attnetion and salience to the pain

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11
Q

Gate control theroy

A

Can only handle so much stimulus so if you stimulate Abeta fibers, less capacity to send pain

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12
Q

TENS

A

Transcutaneous electricla nerve stimuloation

Based on Gate theory

For Chronic MSK pain normally

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13
Q

Opioid indication

A

Acute, traumatic, post op, cancer, palliative

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14
Q

What should especially not be prescribed with opioids

A

Benzos

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15
Q

Opioid receptors

A

Mu - most analgesia and bad things
Kappa - some analgesia, dysphoric effects

Delta - no analgesia

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16
Q

Fentanyl onset of action

A

2-5 minutes

Better than morphine or hydromorphone

17
Q

Naloxone with SE

A

Shorter half life than opioid

Confusion, dizzy, N/V
Arrythmias
Seizures
Negative pressure pulooanry edema

18
Q

Complex regional pain syndrome

A

Hyperaesthesia or allodynia
Temperatuee or skin color asymmetry
Sweating, swelling or atrophy

19
Q

2 types of CRPS

A

RSD - absence of definable injury…noxoius event iwht sponatneous pain and hyperalgesia

Casalgia - Similar course with burning and allodynia…need specific nerve injury

20
Q

Tx of CRPS

A

All physical therapy related

21
Q

Sympathetic blockade success

A

Horner syndrome
Temp increase
Increased blood flow

22
Q

Trigeminal nerualgia and causes

A

Sudden stabbing pain or more constant buring pain that is severe to soft touch

Myelin destruction (BV or MS)
Compression from tumor or AVM
23
Q

Main drug for TN and stuff about it

A

Carbamazepine (Na channel blocker)

Diagnositc for TN

Also for tonic-clonic seizures and bipolar disorder

Stabilizes inactivsated V gated channel

Side effects of SJS, toxic epidermal necrolysis, bone marrow suppression

24
Q

Diabetic peripheral neuroapthy

A

Diagnose with PE, NOT EMG

25
Pregablin
Alpha 2 delta subunit calcium channel blocker More potent and quikcer onset than gabapentin For diabetic and fibromyalgia Dizziness, sleepiness, swelling
26
Gabapentin
Less potent and longer titration period than pregablin
27
Fibromyalgia and tx
Physical, mental, and social components More in women Widespread pain/abnormal pain processing Duloxetine/milnacripran/pregablin
28
Duloxetine
SNRI serotinin-NE reuptake inhibitor Favors serotnin over NE Suicidal thoughts a risk when initating tx in adolescents
29
TCAs
Inhibit serotinin and NE as well as partial Na channel blockade
30
Acute Mechanical LBP
Most gets better Ice, rest, heat NSAIDs, PT
31
Mechanical back pian tx.
Duloxetine or injections
32
Thalamic pain syndrome
Dejerine-Roussy syndrome After thalamic stroke Try everything
33
Intrathecal drugs
Morphine and baclofen (for spasticity) | Ziconotide (Ca hcnanel blocker)