Cerebellum Flashcards
Cerebellum does
Motor planning
Balance, postural adjustment
Correction of ongoing voluntary movements
Also gets non con propripoception from muscle spindles and golgi tendons
Fissures
Primary - separates anterior and posterior
Posterolateral - separates body from flocculonodular lobe
Medial and lateral regions
Vermis - lungula rostral and nodule caudal
Lateral - hemispheres with an intermediate and lateral part
Efferents from cerebellum
Superior - to contralateral thalamus and contralateral brainstem (red nucleus and vest nuclei_)
INferior - ipsilateral brainstem (minimal to vestib nuclei)
Superior and middle affarents
Sup - from ipsi spinal cord (ASCT)
Middle - from contralateral cortex via pontine nuclei (pontocerebellar tract)
Inferior affarents
Ipsi spinal cord (PSCT)
Ipsi BS - Lateral cuneate nucleus, vestibular nuclei, RF
Contra BS via inferior olive
Molecular layer `
Parallel fibers = axcons of granule cells
Dendrites of underlying P cells
Stellate and basket cells carry inhibitory tone
Purkinje layer
Purkinje cell bodies (GABA)…2D
Sole output of cerebellar cortex to white matter of cerebellum
Granular layer
Granule cells - excitatory to all other kinds of cells…become parallel fibers
A few larger golgi cells (GABA)
Layers of input for pons, spinal cord, brainstem, IO
All go to granular later granule cells except for IO (climbing fibers) that go straight to Purkinje cells
Mossy fibers and sources
Rgulate Purkinje neurons indirectly via synaptic contact with granule cells and paralell fibers
Contralateral pontocerebellar
Ipsi Spinocerebellar, cuneocerebellar, vestbiulocerebellar, reticulocerebellar
Climbing fibers and sources
Regulate Purkinjie neurons via direct contract
Contralateral IO as olivocerebellar
IO affarnets
Cortex
RN
Contralateral spinal cord (primary from muscle spindles)
Compares motor info from RN and cortext operiphery
IO efferents
Olivocerebellar fibers to the inferior cerebellar peduncle which modify efficiency and produce LT changes in cerebellar iutput
Nuclei of the spinal cord from lateral to medial and inputs
Dentate - Inputs from cortex via pontine
Interposed - inputs from spinal cord and lateral cuneate nucleus
Fastigial nucleus - inputs from VN, RF